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  • Hybrid technology in many crops has contributed 20-30 per cent increase in the production and exploitation of heterosis through the development of F1 hybrids which has been recently deployed in rice with yield advantage of 20-25 per cent over best pure lines. The main aim of any plant breeding programme is to develop special high yielding hybrids and success of any plant breeding programme depends on the choice of appropriate genotypes as parents in the hybridization programme.

    pdf13p angicungduoc6 22-07-2020 26 2   Download

  • TheST2gene, which is specifically induced by growth sti-mulation in fibroblasts, encodes interleukin-1 receptor-rela-tedproteins and iswidely expressed in hematopoietic, helper T, and various cancer cells. However, the physiological as well as pathological functions of the ST2 gene products are not yet fully understood. In this study, we analyzed the expression of theST2gene in human glioma cell lines and human brain tumor samples with real-time polymerase chain reactionmethod,

    pdf8p tumor12 20-04-2013 48 4   Download

  • Galactokinase (EC 2.7.1.6) catalyzes the first committed step in the catabolism of galactose. The sugar is phosphor-ylated at position 1 at the expense of ATP. Lack of fully functional galactokinase is one cause of the inherited disease galactosemia, the main clinical manifestation of which is early onset cataracts. Human galactokinase (GALK1) was expressed in and purified fromEscherichia coli.The recom-binant enzyme was both soluble and active.

    pdf8p fptmusic 16-04-2013 40 3   Download

  • We report here thatEscherichia coli pyrophosphatase aggregates in the presence of millimolar Cd 2+ . This highly cooperative process was specific to both the metal ion and the protein and could be reversed fully by decreasing the Cd 2+ concentration. Aggregation was enhanced by Mg 2+ , the natural cofactor of pyrophosphatase, and Mn 2+ . Mutations at the intersubunit metal-binding site had no effect, whereas mutation at Glu139, which is part of the peripheral metal-binding site found in pyrophosphatase crystals near the contact region between two enzyme mole-cules, suppressed aggregation.

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  • The pulmonary surfactant prevents alveolar collapse and is required for normal pulmonary function. One of the important components of the surfactant besides phos-pholipids is surfactant-associated protein C (SP-C). SP-C shows complex oligomerization behavior and a transition to b-amyloid-like fibril structures, which are not yet fully understood. Besides this nonspecific oligomerization, MS and chemical cross-linking data combined with CD spectra provide evidence of a specific, mainlya-helical, dimer at lowto neutral pH....

    pdf7p dell39 03-04-2013 46 4   Download

  • Adecrease in the level ofO-acetylatedsialicacidsobserved in colorectal carcinoma may lead to an increase in the expres-sion of sialyl Lewis X , a tumor-associated antigen, which is related toprogressionof colorectal cancer tometastasis. The underlyingmechanism for this reduction is, however, not fully understood. Two enzymes are thought to be primarily responsible for the turnover of O-acetyl ester groups on sialic acids; sialate-O-acetyltransferase (OAT) and sialate-O-acetylesterase (OAE).

    pdf10p dell39 03-04-2013 64 5   Download

  • Palytoxin is a marine toxin responsible for a fatal type of poisoning in humans named clupeotoxism, with symptoms such as neurologic distur-bances. It is believed that it binds to the Na + ⁄K + -ATPase from the extra-cellular side and modifies cytosolic ions; nevertheless, its effects on internal cell structures, such as the cytoskeleton, which might be affected by these initial events, have not been fully elucidated.

    pdf14p galaxyss3 19-03-2013 48 4   Download

  • PUBLIC & PRIVATE MANAGEMENT: FUNDAMENTALLY ALIKE OR DIFFERENT? We can imagine as a thought experiment fully decentralizing school governance in Miami-Dade County, which is served by a single district.53 Figure 1.7 displays the actual distribution of peer groups and school average SAT scores in Miami, as well as the counterfactual distribution that might be observed if the Miami choice index were changed to one and if the effect of choice were at the upper limit of its confidence interval.

    pdf372p mualan_mualan 25-02-2013 50 6   Download

  • Navigating the migration of circuit switched to packet switched networks is a complex affair. In pursuit of improving overall network efficiency and making advanced data services available, service providers must simultaneously protect existing TDM revenue while investing in new packet-based technologies. The good news is that the circuit switched architecture, which accounts for the bulk of service provider revenues, is highly reliable. The bad news is that this massive centralized processing network is neither fully depreciated nor built for packet switching.

    pdf8p qd-tek 28-04-2010 109 7   Download

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