AFTER THE KIDNEY TRANSPLANT – THE PATIENTS AND THEIR ALLOGRAFT

An additional factor for lack of better therapeutic choices is the lack of suitable animal models to replicate human glomerular injury in order to develop and test novel treatment strategies. There are three detailed chapters that exemplify the recent advances in using animal models to explore the pathogenesis of glomerulonephritis. Immunopathogenic mechanisms in a murine model of membranous nephropathy are discussed by Chia-Chao Wu et al., while autoimmune glomerulonephritis complicating chronic graft versus host reaction was discussed by Elena Goiman et al....