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INTRODUCTION
Hepatocellular carcinoma (HCC) is a very popular disease in the
world. According to GLOBOCAN data in 2018, HCC is the fifth and the
ninth most commonly diagnosed cancer in men and women, respectively.
There will usually be an estimated 841,000 new diagnosed cases of HCC
and 782,000 died cases. In Vietnam, According to GLOBOCAN data in
2018, the prevalence and mortality of HCC is one of the first commonly
cancer. The mortality of HCC has their equivalence to compare with new
diagnosed cases, this show that HCC were often diagnosed at advance
stages, so the prognose and control of the disease still have difficulties.
The prognose of HCC is often very poor, especially, they are
advance HCC with portal vein thrombosis (PVT). Previous studies show
that HCC with PVT acount for 30-62.2%, the PVT also is signal point out
that primary HCC is a advance HCC with poor prognosis, risk of
oesophagus variceal bleeding, and hepatic failure (e.g. thrombosis in trunk
of portal vein). Mean survival time of pateints with HCC having PVT
without treatment is very short (2.7-4 months), meanwhile that of HCC
having not PVT without treatment is 24.4 months. Detection of PVT,
especailly benign or neoplastic PVT in new diagnosed HCC has key
meaning for prognosis as well as making choice of treatment methods.
There are no any work to study systematicaly characteristics of
histopathology and immunohistochemistry of PVT in patients with HCC in
Vietnam as well as in the world. From the mention above, we carried out
the project with objectives:
1- assessment of clinical characteristics, paraclinical tests, imaging
diagnoses of HCC pateints with PVT
