Involvement of the CB2 cannabinoid receptor in cell growth inhibition and G0/ G1 cell cycle arrest via the cannabinoid agonist WIN 55,212–2 in renal cell carcinoma

The anti-tumor properties of cannabinoids have been investigated in many in vitro and in vivo studies. Many of these anti-tumor effects are mediated via cannabinoid receptor types 1 and 2 (CB1 and CB2), comprising the endocannabinoid system (ECS).