Evaluating the sub-chronic toxicity of the Boga -TN tablets in experimental animals

The study was carried out in Wistar rats for 4 consecutive weeks by oral administration at the doses of 0.77 and 2.32g/kg/day. After treatment, no significant treatment-related abnormalities were observed at both doses of Boga-TN, compared to the control group, except for the white blood cells, with lower neutrophil but higher lymphocyte values observed in the treated animals. Histopathology assessment did not show any significant variation between control and treatment groups during the study period.