In their conceptions and explanations of illness and in their reactions
to it, individuals and groups attempt, and expect, to be coherent.
They try to present a view which makes sense to themselves and
which is also clear to others who may find it difficult to understand
why healers, patients and other interested parties follow a particular
line of reasoning. When these arguments are seen by contemporaries
to be well founded, this can often be taken as a sign of conformity to
an acceptable form of reasoning which fits into a particular ‘cultural
By the early 1870's, leading figures from both the health professions and the general public had begun to
realize the necessity for having the medical sciences represented in the Smithsonian Institution. The impetus
behind this new feeling resulted from the action of a distinguished American physician, philanthropist, and
author, Joseph Meredith Toner (1825-1896), and came almost a decade before the integration of a new section
concerned with research and the historical and educational aspects of the healing arts in the Smithsonian
In 1872, Dr.
Fibroblasts play a critical role in chronic inflammation
and wound healing. In this study, a fibroblast growth-stimulating factor was purified from the exudate of car-rageenan-induced inflammation in rats. The purified
protein was a disulfide-linked homodimer. Amino acid
sequence analysis of the peptides generated by cleavage
with cyanogen bromide and proteinase V8 resulted in
identification of the protein as S100A9. Recombinant
S100A9 as well as its disulfide-linked homodimer stimu-lated the proliferation of fibroblasts at a similar con-centration of the purified protein. ...
The urokinase-type plasminogen activator (uPA) receptor (uPAR) has been
implicated in signal transduction and biological processes including cancer
metastasis, angiogenesis, cell migration, and wound healing. It is a specific
cell surface receptor for its ligand uPA, which catalyzes the formation of
plasmin from plasminogen, thereby activating the proteolytic cascade that
contributes to the breakdown of extracellular matrix, a key step in cancer
Vascular endothelial growth factor (VEGF) family members play impor-tant roles in embryonic development and angiogenesis during wound
healing and in pathological conditions such as tumor formation. Parapox-viruses express a new member of the VEGF family which is a functional
mitogen that specifically activates VEGF receptor (VEGFR)-2 but not
Phenoloxidases occur in almost all organisms, being essentially involved in
various processes such as the immune response, wound healing, pigmenta-tion and sclerotization in arthropods. Many hemocyanins are also capable
of phenoloxidase activity after activation.
HR12 is anovel farnesyltransferase inhibitor (FTI).Wehave
shown previously that HR12 induces phenotypic reversion
-transformed Rat1 (Rat1/ras) fibroblasts. This
reversion was characterized by formation of cell–cell con-tacts, focal adhesions and stress fibers. Here we show that
HR12 inhibits anchorage independent and dependent
growth of Rat1/ras cells. HR12 also suppresses motility and
proliferation of Rat1/ras cells, in a wound healing assay.
Rat1 fibroblasts transformed with myristoylated H-ras
(Rat1/myr-ras) were resistant to HR12....
This book provides information on alternative and complementary
therapies that can expand the healing spectrum for
individuals with spinal cord injury (SCI). It discusses healing
perspectives and paradigms that have not been a part of traditional
modern medicine but that, nevertheless, comprised a key component
of healing armamentaria throughout much of mankind’s history.
As health care providers, we spend our lives searching for treatments
that reduce suffering and lengthen the lives of our patients. Sometimes
we find solutions in surprising places. Although we all have hopes for
advancements in technology, the future of medicine is also about
challenging preconceptions as we change our healing biases. In many
ways, this is the natural evolution of “global medicine.” We have global
communications and global banking; however, until recently medicine
has remained remarkably provincial.
Most books on house rabbits are written as a result of
the author’s personal experience with a rabbit companion.
This book is no exception. I first conceived
the idea of writing about disabled buns after my experiences
with a rabbit who required constant specialized care. He inspired
me to write an article about caring for special-needs
rabbits, which appeared online, and I then planned to expand
the topic into a book.
My primary purpose in writing and revising this book has been to provide
an updated introduction to the history of medicine. Although the
text began as a ‘‘teaching assistant’’ for my own one-semester survey
course, I hope that this new edition will also be of interest to a general
audience, and to teachers who are trying to add historical materials to
their science courses or science to their history courses.
The preliminary work consisted of archival literature and organizational searches.
Conferences on the topic of traditional medicine were hosted across North America,
including New Mexico, Arizona, British Columbia, and Washington. These were key
opportunities to attend conferences that yielded a great deal of information on the subject
of traditional medicine. The resultant discussions raised themes that ranged from
government policy to contemporary implementations of strategies used by both healers and
Indigenous medical practitioners.
Traditional healing has been defined as “practices designed to promote mental,
physical and spiritual well-being that are based on beliefs which go back to the
time before the spread of western ‘scientific’ bio-medicine. When Aboriginal
Peoples in Canada talk about traditional healing, they include a wide range of
activities, from physical cures using herbal medicines and other remedies, to the
promotion of psychological and spiritual well-being using ceremony, counseling
and the accumulated wisdom of elders (RCAP, 1996, Vol.3: 348). ...
Only recently have Indigenous Peoples in North America begun to revitalize traditions
openly and without fear of persecution. We must remember that it is only since the 1970s
that legal bans on healing/religious ceremonies such as the Sundance have been lifted.
This Indigenous literature is often found outside of academia and within Native
organizations and their resource libraries, research reports (founded either by government
or community bodies) and Web sites such as American Indian Physicians Association, the
World Health Organization and Pan American Health Organization.
While discussing traditional health practices and medical knowledge, one could
expect elders to give a list of the best techniques to cure sickness depending on the
various types of health problems or injuries they were facing in the past: how to
deal with boils, infections, fever, eye infections, colds, broken bones, drowning,
and so on. But the Inuit perspective encompasses much more. Along with
techniques to heal cuts and wounds, and to cure sickness...elders discussed
recollections of how to have a strong mind and a resilient body....
As the modern era has ended formal assimilation policies and introduced multicultural
policies that support Indigenous traditionalism, an interesting challenge is now faced by
Indigenous Peoples, the institutionalization of tradition! (RCAP, 1996; Waldrum, 1997;
Frideres, 1993). The fact that government agencies “support” the revitalization of
Aboriginal “culture and heritage” creates the need to analyze what kind of impact these
new policies will have on specific areas, most critically, traditional medicine.