Báo cáo khoa học: Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract
ADH1 and ADH4 are the major alcohol dehydrogenases
(ADH) in ethanol and retinol oxidation. ADH activity and
protein expression were investigated in rat gastrointestinal
tissuehomogenates by enzymatic andWesternblot analyses.
In addition, sections of adult rat gastrointestinal tract were
examined byin situ hybridization and immunohistochem-istry.ADH1andADH4weredetectedalong thewhole tract,
changing their localization and relative content as a function
of the area studied.
