báo cáo khoa hoc : Spatial structure peculiarities of influenza A virus matrix M1 protein in an acidic solution that simulates the internal lysosomal medium

The structure of the C-terminal domain of the influenza virus A matrix M1 protein, for which X-ray diffraction data were still missing, was studied in acidic solution. Matrix M1 protein was bombarded with thermally-acti-vated tritium atoms, and the resulting intramolecular distribution of the tri-tium label was analyzed to assess the steric accessibility of the amino acid residues in this protein.