Kết quả sớm phẫu thuật cắt toàn bộ bàng quang, chuyển lưu nước tiểu kiểu Bricker điều trị ung thư bàng quang tại Bệnh viện Trung ương Quân đội 108

Bladder cancer represents a significant global health challenge, standing as the second most common malignancy of the urinary system. For patients with locally advanced bladder cancer, radical cystectomy followed by urinary diversion is a cornerstone of curative treatment. Among the various diversion techniques, Bricker's urinary diversion has been widely adopted as a standard procedure due to its established efficacy. Despite its importance, comprehensive data on the early outcomes of radical cystectomy with Bricker's urinary diversion, particularly within specific regional medical centers, remains limited. This study aims to fill this knowledge gap by evaluating the early results of radical cystectomy and Bricker's urinary diversion for bladder cancer patients at 108 Military Central Hospital, thereby contributing valuable insights into the procedure's local effectiveness and safety.

Medical professionals, including urologists, oncologists, surgeons, and researchers involved in the treatment and management of bladder cancer.

This retrospective study evaluated the early outcomes of radical cystectomy and Bricker's urinary diversion in 40 patients with locally advanced bladder cancer at 108 Military Central Hospital between March 2021 and May 2024. The findings revealed a mean age of 66.89 years, with a predominant male patient population. Surgical procedures demonstrated a mean operation time of 245.38 minutes and a Bricker's diversion time of 136.63 minutes. While intraoperative blood transfusion occurred in 12.5% of cases, no organ damage or intraoperative mortality was reported. The mean postoperative hospital stay was 11.5 days. Overall, 22.5% of patients experienced postoperative complications, primarily lymphatic leakage (7.5%), wound infection (5%), and urinary leakage (2.5%), with a 3-month mortality rate of 5%. Follow-up observations also indicated instances of reduced kidney function and hydronephrosis. The study concludes that radical cystectomy followed by Bricker's urinary diversion, though a complex surgery associated with potential complications, is an effective and relatively safe treatment option for locally advanced ung thư bàng quang. These results contribute valuable local evidence, reinforcing the importance of this procedure in managing bladder cancer and guiding clinical practice, particularly given the challenges associated with complex surgical interventions like cắt toàn bộ bàng quang and chuyển lưu nước tiểu kiểu Bricker.