Associations of single nucleotide polymorphism rs17782313 in melanocortin 4 receptor gene with anthropometric indices in normal and obesity primary school children in Hanoi
The results show that in the normal group, the data of z score of weight for age was the highest in CC genotype group and was the lowest in TT genotype group (0.11 and -0.38, respectively, p=0.023). In the obese group, the waist hip ratio was the lowest in TT genotype group and the highest one was in CC genotype group (0.93 and 0.97 respectively, p=0.031). The study findings indicate that variant rs17782313 of MC4R is likely to have an impact on the changing of weight and central obesity in the Vietnamese children.