Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
This work proposes a model of the metabolic branch-point
between the methionine and threonine biosynthesis path-ways inArabidopsis thalianawhich involves kinetic compe-tition for phosphohomoserine between the allosteric enzyme
threonine synthase and the two-substrate enzyme cysta-thionine c-synthase. Threonine synthase is activated by
S-adenosylmethionine and inhibited by AMP. Cystathio-ninec-synthase condenses phosphohomoserine to cysteine
via a ping-pong mechanism.
