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The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer

In breast cancer (BC), recurrent fusion genes of estrogen receptor alpha (ESR1) and AKAP12, ARMT1 and CCDC170 have been reported. In these gene fusions the ligand binding domain of ESR1 has been replaced by the transactivation domain of the fusion partner constitutively activating the receptor.

vikolindagrabar

27/07/2022

BMC Cancer Fusion genes Breast cancer Multivariable analysis Disease free survival

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Optimization of the flow cytometric method for analyzing NK cell cytotoxic activity in breast cancer

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Adherence to adjuvant endocrine therapy and associated factors among patients with breast cancer

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Molecular docking study of anticancer activity of some s-triazine derivatives as HDAC6 inhibitors

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Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt

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Báo cáo Y học: Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis

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Báo cáo Y học: Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1

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Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis

Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis

Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine

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Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider

Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider

Báo cáo Y học: Stabilization of a (ba)8-barrel protein by an engineered disulﬁde bridge

Báo cáo Y học: Stabilization of a (ba)8-barrel protein by an engineered disulﬁde bridge

Báo cáo Y học: Chemical structure and immunoreactivity of the lipopolysaccharide of the deep rough mutant I-69 Rd–/b+ of Haemophilus inﬂuenzae

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Báo cáo Y học: Exploration of the diaphorase activity of neutrophil NADPH oxidase Critical assessment of the interaction of iodonitrotetrazolium with the oxidase redox components

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Báo cáo Y học: Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family

Báo cáo Y học: Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family

Báo cáo Y học: The role of hydrophobic active-site residues in substrate speciﬁcity and acyl transfer activity of penicillin acylase

Báo cáo Y học: The role of hydrophobic active-site residues in substrate speciﬁcity and acyl transfer activity of penicillin acylase

Báo cáo Y học: The mitochondrial-lysosomal axis theory of aging Accumulation of damaged mitochondria as a result of imperfect autophagocytosis

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Báo cáo Y học: Activation of a covalent outer membrane phospholipase A dimer

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Báo cáo Y học: The amyloid precursor protein interacts with neutral lipids Liposomes and monolayer studies

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Báo cáo Y học: Molecular and biochemical characteristics of a gene encoding an alcohol acyl-transferase involved in the generation of aroma volatile esters during melon ripening

Báo cáo Y học: Molecular and biochemical characteristics of a gene encoding an alcohol acyl-transferase involved in the generation of aroma volatile esters during melon ripening

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