Analysis and channel

The objectives to be achieved from this research are Analyzing channels and the efficiency of marketing the catch of marine products of local fishermen in Malind District, Merauke Regency. The method used in this study is Survey.

7p lucastanguyen 01-06-2020 15 2   Download

This study investigates men and women’s representations in TV advertisements in Vietnam from a multimodal critical discourse analysis perspective. The data comprise of almost one hundred TV advertisements aired on principle TV channels in Vietnam such as VTV and HTV. The framework in use is Fairclough’s (2001), in which part of Kress and van Leeuwen’s visual grammar (1996) is incorporated for a multimodal discourse analysis of the advertisements.

70p nguathienthan 04-10-2019 42 1   Download

Learning objectives: Understand the central role played by end-users and their demands in the design of marketing channels, define “service outputs” and identify and analyze them, recognize how to divide a market into channel segments for the purposes of marketing channel design or modification, understand how to target channel segments to optimize sales and profits.... and other contents.

6p tieu_vu08 05-05-2018 40 2   Download

Learning objectives: Understand vertical integration as a continuum from make to buy rather than as a binary choice, explain why channel players (manufacturers, wholesalers, retailers) often integrate forward or backward with great expectations, only to divest themselves within a few years.... and other contents.

5p tieu_vu08 05-05-2018 41 2   Download

Lecture Marketing channel strategy - Chapter 3: Channel analysis - Auditing marketing channels" has contents: Auditing marketing channels, physical possession, inventory holding costs, information sharing,... And other contents.

10p tieu_vu08 05-05-2018 58 1   Download

When you finish this chapter, you will: Understand how most wholesalers and retailers set their prices using markups, understand why turnover is so important in pricing, understand the advantages and disadvantages of average-cost pricing, know how to use break-even analysis to evaluate possible prices, know the many ways that price setters use demand estimates in their pricing.

10p allbymyself_06 26-01-2016 44 4   Download

This paper proposes an efficient division algorithm protected against simple side-channel analysis. The proposed algorithm applies equally well to software and hardware implementations. Furthermore, it does not impact the running time nor the memory requirements.

10p dunglh2013 02-04-2014 56 1   Download

The function of squalene-hopene cyclase from Alicyclobacillus acidocaldarius was studied by labelling critical cysteine residues of the enzyme, either native or inserted by sitedirected mutagenesis, with different thiol-reacting molecules. The access of the substrate to the active centre cavity through a nonpolar channel that contains a narrow constriction harbouring a cysteine residue (C435) was probed by labelling experiments on both a C435S mutant, lacking C435 of the channel constriction, and a C25S/C50S/C455S/C537S mutant, bearing C435 as the only cysteine residue.

9p research12 01-06-2013 45 3   Download

This review provides a comparative overview of recent developments in the modelling of cellular calcium oscilla-tions. A large variety of mathematical models have been developed for this wide-spread phenomenon in intra- and intercellular signalling. From these, a general model is extracted that involves six types of concentration variables: inositol 1,4,5-trisphosphate (IP3), cytoplasmic, endoplasmic reticulum and mitochondrial calcium, the occupied binding sites of calcium buffers, and the fraction of active IP3 receptor calciumrelease channels....

23p research12 29-04-2013 27 3   Download

Vibrio choleraehemolysin (HlyA), a water-soluble protein with a native monomeric relative molecular mass of 65 000, forms transmembrane pentameric channels in target bio-membranes.TheHlyAbinds to lipid vesicles nonspecifically and without saturation; however, self-assembly is triggered specifically by cholesterol.Here we show that the HlyA partitioned quantitatively to amphiphilic media irrespective of their compositions, indicating that the toxin had an amphiphilic surface.

8p research12 23-04-2013 56 4   Download

Aquaporin adipose (AQPap), which we identi®ed from human adipose tissue, is a glycerol channel in adipocyte [Kishida et al. (2000) J. Biol. Chem.275, 20896±20902]. In the current study, we determined the genomic structure of the human AQPap gene, and identi®ed three AQPap-like genes that resembled (95%)AQPap, with little expression in human tissues.

13p research12 23-04-2013 33 2   Download

ATP-sensitive K + channels are an octameric assembly of two proteins, a sulfonylurea receptor (SUR1)and an ion conducting subunit (Kir 6.0). We have examined the role of the C-terminus of SUR1 by expressing a series of truncation mutants together with Kir6.2 stably in HEK293 cells. Bio-chemical analyses using coimmunoprecipitation indicate that SUR1 deletionmutants andKir6.2 assemble and that a SUR1 deletion mutant binds glibenclamide with high affin-ity.

11p tumor12 22-04-2013 42 4   Download

We previously purified and characterized a peptide toxin, birtoxin, from the South African scorpion Parabuthus transvaalicus. Birtoxin is a 58-residue, long chain neurotoxin that has a unique three disulfide-bridged structure. Here we report the isolation and characterization of ikitoxin, a pep-tide toxin with a single residue difference, and a markedly reducedbiological activity, frombirtoxin. Bioassays onmice showed that high doses of ikitoxin induce unprovoked jumps, whereas birtoxin induces jumps at a 1000-fold lower concentration. ...

8p tumor12 22-04-2013 41 3   Download

The vanilloid-like TRP-channel VRL-1 (TRPV2) is a non-selective cation channel expressed by primary sensory neurons and non-neuronal tissues [Caterina, M.J., Rosen, T.A., Tominaga, M., Brake, A.J and Julius, D. (1999) Nature398, 436–441]. It is one of the six members of the vanilloid-like TRP-channel family which is now termed the TRPV family [Montell, G., Birnbaumer, L., Flockerzi, V., Bindels, R.J., Brutford, E.A., Caterina, M.J., Clapham, D.E., Harteneck, C., Heller, S., Julius, D., Kojima, I., Mori, Y., Penner, R., Prawitt, D., Scharenberg, A.M., Schultz, G., Shimizu, N. and Zhu, M.X.

8p tumor12 20-04-2013 28 3   Download

Several crystal andNMRstructures of calmodulin (CaM)in complex with fragments derived from CaM-regulated pro-teins have been reported recently and reveal novel ways for CaMto interact with its targets. This review will discuss and compare features of the interaction between CaM and its target domains derived from the plasma membrane Ca 2+ -pump, the Ca 2+ -activated K + -channel, the Ca 2+ / CaM-dependent kinase kinase and the anthrax exotoxin.

11p tumor12 20-04-2013 26 4   Download

Crotamine is a component of the venom of the snakeCro-talus durissus terrificusand it belongs to the myotoxin pro-tein family. It is a 42 amino acid toxin cross-linked by three disulfide bridges and characterized by a mild toxicity (LD50¼820lg per 25 g body weight, i.p. injection) when compared to other members of the same family. Nonethe-less, it possesses a wide spectrum of biological functions.

11p fptmusic 16-04-2013 30 2   Download

There is mounting evidence that the vanilloid (capsaicin) receptor; transient receptor potential channel, vanilloid subfamily member 1 (TRPV1), is subjected to multiple interacting levels of control. The first level is by reversible phosphorylation catalyzed by intrinsic kinases (e.g. protein kinase A and C) and phosphatases (e.g. calcineurin), which plays a pivotal role in receptor sensitization vs. tachyphy-laxis.

6p dell39 03-04-2013 45 3   Download

The transient receptor potential channel vanilloid receptor subunit 1 (TRPV1) is amolecular integrator of physical and chemical stimuli in the peripheral nociceptor terminals. TRPV1 is an ionotropic channel that plays a critical role in both thermal nociception and inflammatoryhyperalgesia. Structure–function relationships are providing fundamental insights of the modular architecture of this neuronal recep-tor.

7p dell39 03-04-2013 46 3   Download

Mutational analysis of functional domains in Mrs2p, the mitochondrial Mg2+ chanThe nuclear geneMRS2in Saccharomyces cerevisiaeencodes an integral protein (Mrs2p) of the inner mitochondrial membrane. It forms an ion channel mediating influx of Mg 2+ into mitochondria. Orthologues of Mrs2p have been shown to exist in other lower eukaryotes, in vertebrates and in plants.nel protein of Saccharomyces cerevisiae ` Julian Weghuber, Frank Dieterich, Elisabeth M. Froschauer, Sona Svidova and Rudolf J. Schweyen Max F.

12p inspiron33 26-03-2013 66 5   Download

The nicotinic acetylcholine receptor (AChR) is a ligand-gated ion channel found in muscles and neurons. Muscle AChR, formed by five homologous subunits (a2bcdora2bce), is the major antigen in the autoimmune disease, myasthenia gravis (MG), in which pathogenic autoantibodies bind to, and inactivate, the AChR.

12p inspiron33 25-03-2013 41 2   Download