Colon cancer

Evaluation of feasibility, safety, and outcomes of single port laparoscopic surgery (SPLS) for right hemicolectomy. Prospective study of 84 patients suffering from right colon cancer who underwent SPLS between December 2010 and December 2016 and were followed up until December 2017 in Hue Central Hospital.

7p vinatisu 29-08-2024 5 0   Download

Pembolizumabis an immune check-point inhibitor to be targeted for Programmed cell death 1 (PD-1). It has been shown promising efficacy to various types of cancer. In Vietnam, pembrolizumab has been available since early of 2018. We has performed to treat certain types of cancer with pembrolizumabby now, herein we report the early experience with pembrolizumabin single institute in Vietnam.

4p vinatisu 29-08-2024 5 1   Download

Ovarian cancer constitutes one of the most lethal gynecologic malignancies for females. Currently, early detection strategies and therapeutic options for ovarian cancer are far from satisfactory, leading to high diagnosis rates at late stages and disease relapses. New avenues of therapy are needed that target key processes in ovarian cancer progression.

20p vimichaelfaraday 25-03-2022 16 1   Download

Several studies have demonstrated that the preoperative Glasgow prognostic score (GPS) and modifed GPS (mGPS) refected the prognosis in patients undergoing curative surgery for colorectal cancer. However, there are no reports on long-term prognosis prediction using high-sensitivity mGPS (HS-GPS) in colorectal cancer. Therefore, this study aimed to calculate the prognostic value of preoperative HS-GPS in patients with colon cancer.

11p vielonmusk 21-01-2022 14 1   Download

Peroxisomes are pivotal metabolic organelles that exist in almost all eukaryote cells. A reduction in numbers and enzymatic activities of peroxisomes was found in colon adenocarcinomas. However, the role of peroxisomes or the peroxisome pathway in colorectal cancer (CRC) is not defined.

17p vielonmusk 21-01-2022 12 0   Download

The immune system recognizes and destroys cancer cells. However, cancer cells develop mecha‑ nisms to avoid detection by expressing cell surface proteins. Specific tumour cell surface proteins (e.g. HLA-G, PD-L1, CDX2) either alone or in combination with the relative presence of immune cells (CD3 and CD8 positive T-cells) in the tumour tissue may describe the cancer cells’ ability to escape eradication by the immune system.

19p vielonmusk 21-01-2022 12 1   Download

Activated Cdc42-associated kinase 1 (ACK1), a kind of tyrosine kinase, is considered to be an oncogene in many cancers, and it is likely to become a potential target for cancer treatment. We found that the expression of the ACK1 gene in colon cancer was higher than that in normal tissues adjacent to cancer, and high expression of the ACK1 gene was associated with poor prognosis of patients.

12p vielonmusk 21-01-2022 17 0   Download

Objectives: Assessment of anti-human colon cancer cell (HT-29 cell) efficacy and activating apoptosis of MeV and MuV combination in vitro. Assessment of C cell tumor efficacy of MeV and MuV combination in nude mice xenograft models.

26p petsematary 02-06-2021 7 2   Download

The thesis has two objectives: Determining the degree of lymph node metastasis and characteristics of lymph node dissection technique in laparoscopic surgery for colon cancer. Evaluating the effectiveness of laparoscopic radical surgery for colon cancer and their related factors.

27p petsematary 02-06-2021 17 4   Download

In this paper, we present an overview of the imbalanced data classification and the difficulties encountered in current approaches, from which we propose a new method, SMOTE-PLS. To evaluate the effectiveness of this new method, we conducted experiments based on standard cancer data sets from UCI sources, including breast-p, coil2000, leukemia, colon-cancer, and yeast.

9p koxih_kothogmih5 04-09-2020 4 1   Download

Study the Malondialdehyde content in patients with colon cancer who underwent radical surgery treatment. Evaluate the changes in red blood cell Malondialdehyde content of patients with colon cancer after radical surgery.

30p angicungduoc6 21-07-2020 25 2   Download

Bài viết đề xuất một phương pháp mới, phương pháp kết hợp giảm số chiều thuộc tính bình phương tối thiểu và sinh thêm phần tử nhân tạo SMOTE. Để đánh giá hiệu quả của phương pháp mới này, chúng tôi đã thực nghiệm dựa trên những bộ dữ liệu chuẩn từ nguồn UCI đó là: leukemia, breast-p, coil, colon-cancer.

9p vihasaki2711 13-11-2019 36 2   Download

Group IID secretory phospholipase A2 (sPLA2-IID), a heparin-binding sPLA2 that is closely related to sPLA2-IIA, augments stimulus-induced cellular arachidonate release in a manner similar to sPLA2-IIA. Here we identified the residues of sPLA2-IID that are responsible for heparanoid binding, are and therefore essential for cellular function.

10p system191 01-06-2013 36 5   Download

Matrilysin (matrix metalloproteinase-7) plays important roles in tumor progression. It was previously found that matrilysin binds to the surface of colon cancer cells to promote their metastatic potential. In this study, we identified annexin II as a novel membrane-bound substrate of matrilysin. Treatment of human colon cancer cell lines with active matrilysin released a 35 kDa annexin II form, which lacked its N-terminal region, into the culture supernatant. The release of the 35 kDa annexin II by matrilysin was significantly enhanced in the presence of serotonin or heparin....

14p research12 29-04-2013 39 2   Download

We determined differentially expressed genes in HT29 human colon cancer cells, both after short treatment with methotrexate (MTX) and after the resistance to MTX had been established. Screening was performed using Atlas Human Cancer 1.2K cDNA arrays. The analysis was carried out using Atlasimage 2.01 andgenespring6.1 software.

15p awards 05-04-2013 31 1   Download

N-6 polyunsaturated fatty acids (PUFAs) may be associated with increased risk of colon cancer, whereas n-3 PUFAs may have a protective effect. We examined the effects of docosahexaenoic acid (DHA), eicosapentaenoic acid and arachidonic acid on the colon carcinoma cell lines SW480 derived from a primary tumour, and SW620 derived from a metastasis of the same tumour.

17p dell39 27-03-2013 34 4   Download

Galloylated and nongalloylated catechin conjugates with cysteine deriva-tives have been synthesized and evaluated for their capacity to scavenge free radicals and to influence crucial functions (cell cycle, apoptosis) in HT29 colon carcinoma cells. We show that the nonphenolic part of the molecule modified the capacity of catechins to donate hydrogen atoms and to transfer electrons to free radicals.

12p inspiron33 26-03-2013 34 4   Download

Human colon adenocarcinoma cells (HT29-ATCC) and the clone HT29-5F7 were cultured under conditions that differentiate cells to a polarized intestinal phenotype. Differentiated cells showed the presence of junctional complexes and intercellular lumina bordered by microvilli. Intestinal brush border hydrolase activities (sucrase, aminopeptidase N, lactase and mal-tase) were detected mainly in differentiated HT29-ATCC cells compared with the differentiated clone, HT29-5F7.

10p inspiron33 25-03-2013 37 3   Download

Physalis philadelphicaLam, commonly known as a tomatillo, is a staple of the Mesoamerican cuisine. In our laboratory, an ethyl acetate-soluble extract and four withanolides [ixocarpalactone A (IxoA), ixocarpalac-tone B, philadelphicalactone B, and withaphysacarpin] were isolated. Stud-ies conducted on Hepa-1c1c7 hepatoma cells revealed that withanolides were potent inducers of quinone reductase, suggesting possible cancer chemo-protective activity.

10p inspiron33 23-03-2013 36 3   Download

Grape (Vitis vinifera) and pine (Pinus pinaster) bark extracts are widely used as nutritional supplements. Procyanidin-rich fractions from grape and pine bark extract showing different mean degrees of polymerization, per-centage of galloylation (percentage of gallate esters) and reactive oxygen species-scavenging capacity were tested on HT29 human colon cancer cells.

10p media19 04-03-2013 39 3   Download