Essential requirement

This study examines the skills required for individuals to thrive in the digital economy and emphasizes the significance of education and training in developing these skills. The article concludes by emphasizing the importance of equipping individuals with the necessary skills to succeed in the digital economy, and suggests future research directions.

9p viyamanaka 06-02-2025 3 2   Download

The article evaluates factors affecting the stability of the financial system in Vietnam. Because of many unpredictable fluctuations, significantly affecting trade and investment activities, financial stability is always an essential requirement for Vietnam to ensure the healthy development of the economy.

6p tuetuebinhan000 23-01-2025 3 2   Download

Define the problems, decide the objectives of business in the short and in the long run, estimate the available and potential resources… Determine the tasks, activities and projects, programs...and require for the attainment of objectives. Formulate the policies, procedures, methods, standard and budgets of the plan. Examine the environmental changes, reconsider continually, searching the essential information constantly for more effective methods and improve results.

40p tuonglinh2112 05-08-2013 91 7   Download

Housing is an essential amenity. However the impact, due to current trend of increasing embodied energy consumption per capita should be minimised. This may even require major cultural shift to traditional construction processes, practices and home owner perceptions. This thesis presents the outcomes of a study investigating ways to produce a “bill of embodied energy” for housing sector aligned to the standard practice of “bill of quantities”.

260p runthenight07 01-03-2023 8 3   Download

In Lecture "Introduction to software engineering - Week 1: Course introduction", you will learn to: A general introductory course in software engineering; Introduces important concepts such as software processes and agile methods, and describes essential software development activities, from initial software specification through to system evolution; develop software in multi-person teams by applying software engineering principles.

11p larachdumlanat 09-11-2020 21 3   Download

Development of anthelmintic resistance has made it essential to develop alternative ways of worm control in animals. One of the most promising approaches is to treat only those animals which require attention in terms of worm management. “FAMACHA” method has facilitated quick identification of Haemaonchus contortus infected sheep and goats without the aid of any laboratory procedures and delivers the treatment only to those who require it.

6p angicungduoc6 22-07-2020 35 4   Download

Transformational leadership theory is an essential topic in management research. This style of leadership requires a leader's ability to identify and observe the psychological needs and values of followers, as well as to stimulate work motivation.

11p christabelhuynh 04-06-2020 21 3   Download

Trehalose metabolism is an essential component of the stress response in yeast cells. In this work we show that the products of the principal genes involved in trehalose metabolism in Schizosaccharomyces pombe, tps1+ (coding for trehalose6-P synthase, Tps1p), ntp1+ (encoding neutral trehalase, Ntp1p) and tpp1+ (that codes for trehalose-6-P phosphatase, Tpp1p), interact in vitro with each other and with themselves to form protein complexes. Disruption of the gene tps1+ blocks the activation of the neutral trehalase induced by heat shock but not by osmotic stress.

9p system191 01-06-2013 28 4   Download

Cytidine in the anticodon second position (position 35) and G or U in position 36 of tRNAArg are required for aminoacylation by arginyl-tRNA synthetase (ArgRS) from Escherichia coli. Nevertheless, an arginine-accepting amber suppressor tRNA with a CUA anticodon (FTOR1D26) exhibits suppression activity in vivo [McClain, W.H. & Foss, K. (1988) Science, 241, 1804 –1807]. By an in vitro kinetic study with mutagenized tRNAs, we showed that the arginylation of FTOR1D26 involves C34 and U35, and that U35 can be replaced by G without affecting the activity.

7p system191 01-06-2013 24 3   Download

Duodenase is a 29-kDa serine endopeptidase that displays selective trypsin- and chymotrypsin-like substrate specificity. This enzyme has been localized to epitheliocytes of Brunner’s glands, and as described here, to mast cells within the intestinal mucosa and lungworm-infected lung, implying an important additional role in inflammation and tissue remodelling. In primary cultures of pulmonary artery fibroblasts, duodenase induced a concentration-dependent increase in [3H]thymidine incorporation with a maximal effect observed at 30 nM.

10p research12 01-06-2013 57 3   Download

The core complex ofRhodobacter sphaeroidesis formed by the association of the light-harvesting antenna 1 (LH1) and the reaction center (RC). The PufX protein is essential for photosynthetic growth; it is locatedwithin the core in a 1 : 1 stoichiometry with the RC. PufX is required for a fast ubiquinol exchange between the QBsite of the RC and the Qo site of the cytochromebc1complex.

9p research12 23-04-2013 34 3   Download

Era is a highly conserved GTPase essential for bacterial growth. The N-terminal part of Era contains a conserved GTPase domain, whereas the C-terminal part of the protein contains anRNA- andmembrane-binding domain, theKH domain. To investigate whether the binding of Era to 16S rRNA and membrane requires its GTPase activity and whether the GTPase domain is essential for these acti-vities, the N- and C-terminal parts of the Streptococ-cus pneumoniaeEra –Era-N(aminoacids 1–185) andEra-C (amino acids 141–299), respectively – were expressed and purified. ...

9p tumor12 20-04-2013 34 3   Download

Four pyruvate dehydrogenase kinase and two pyruvate dehydrogenase phosphatase isoforms function in adjusting the activation state of the pyruvate dehydrogenase complex (PDC) through determining the fraction of active (non-phosphorylated) pyruvate dehydrogenase component. Necessary adaptations of PDC activity with varying meta-bolic requirements in different tissues and cell types are met by the selective expression and pronounced variation in the inherent functional properties and effector sensitivities of these regulatory enzymes. ...

7p tumor12 20-04-2013 32 2   Download

Ribonucleotide reductase is essential for the synthesis of all four dNTPs required for DNA replication. The enzyme is composed of two proteins, R1 and R2, which are both needed for activity. Expression of the R1 andR2mRNAs is restricted to the S-phase of the cell cycle, but the R1 andR2 promoters shownoobvious sequence homologies that could indicate coordination of transcription.

11p fptmusic 16-04-2013 40 3   Download

In eukaryotes, pre-rRNA processing depends on a large number of non-ribosomal trans-acting factors that form large and intriguingly organized complexes. A novel nucleolar protein, Nop53p, was isolated by using Nop17p as bait in the yeast two-hybrid system. Nop53p also interacts with a second nucleolar protein, Nip7p. A carbon source-conditional strain with the NOP53coding sequence under the control of theGAL1promoter did not grow in glucose-containing medium, showing the phenotype of an essential gene. ...

14p fptmusic 11-04-2013 33 2   Download

Addition of the second mannose is the only obvious step in glycosylphos-phatidylinositol (GPI) precursor assembly for which a responsible gene has not been discovered. A bioinformatics-based strategy identified the essential Saccharomyces cerevisiaeYbr004c protein as a candidate for the second GPIa-mannosyltransferase (GPI-MT-II). S. cerevisiae cells depleted of Ybr004cp have weakened cell walls and abnormal morphology, are unable to incorporate [ 3 H]inositol into proteins, and accumulate a GPI intermedi-ate having a single mannose that is likely modified with ethanolamine phosphate. ...

9p awards 05-04-2013 31 3   Download

Glutamine is an essential amino acid in cancer cells and is required for the growth of many other cell types. Glutami-nase activity is positively correlated with malignancy in tumours andwith growth rate in normal cells. In the present work, Ehrlich ascites tumour cells, and their derivative, 0.28AS-2 cells, expressing antisense glutaminase mRNA, were assayed for apoptosis induced by methotrexate and hydrogen peroxide. It is shown that Ehrlich ascites tumour cells, expressing antisense mRNA for glutaminase, contain lower levels of glutathione than normal ascites cells. In addition, 0.

9p awards 05-04-2013 47 4   Download

Gas1p is a glycosylphosphatidylinositol-anchored plasma membrane glycoprotein ofSaccharomyces cerevisiaeand is a representative of Family GH72 of glycosidases/transgly-cosidases, which also includes proteins from human fungal pathogens. Gas1p, Phr1-2p from Candida albicansand Gel1p fromAspergillus fumigatushave been shown to be b-(1,3)-glucanosyltransferases required for proper cell wall assembly andmorphogenesis. Gas1p is organized into three modules: a catalytic domain; a cys-richdomain; andahighly O-glycosylated serine-rich region. ...

11p awards 05-04-2013 48 4   Download

During biosynthesis of chlorophyll, Mg 2+ is inserted into protoporphyrin IX by magnesium chelatase. This enzyme consists of three different subunits of
40, 70 and 140 kDa. Seven barley mutants deficient in the 40 kDa magnesium chelatase subunit were analysed and it was found that this subunit is essential for the maintenance of the 70 kDa subunit, but not the 140 kDa subunit. The 40 kDa subunit has been shown to belong to the family of proteins called
ATPases associated with various cellu-lar activities, known to form ring-shaped oligomeric complexes working as molecular chaperones....

7p dell39 03-04-2013 31 4   Download

The ability to predict the function of a protein, given its sequence and⁄or 3D structure, is an essential requirement for exploiting the wealth of data made available by genomics and structural genomics projects and is there-fore raising increasing interest in the computational biology community.

7p inspiron33 25-03-2013 39 3   Download