Molecular biology

The main components of black ginger (Kaempferia parviflora Wall ex Baker.) show diverse biological effects, especially potential ancancer activity. Thirty-five bioactive compounds were screened for ancancer activity by molecular docking with AutoDock Vina software on VEGFR2 kinase.

10p viling 11-10-2024 0 0   Download

Encephalitis - meningitis today is still a serious public health problem with a high mortality rate. To describe the clinical and subclinical characteristics of encephalitis-meningitis caused by Varicella zoster virus (VZV) in people from 15 years old.

8p vifaye 20-09-2024 10 2   Download

The thesis is organised as follows: Chapter 1 comprises the literature review of protein structure, amyloid fibrils and of the effect of nanomaterials on protein aggregation. Chapter 2 reviews the computational methods used to perform simulations and analysis. Chapter 3 comprises my published article on benchmarking forcefields and sampling methods for disordered proteins using amylin as a case study. Chapter 4 comprises my published article on the effect of oxidation on the properties of graphene oxide flakes in solution.

56p runthenight04 02-02-2023 12 3   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 5 3   Download

A new study reveals comprehensive and unique epigenetic properties of glioma stem cells, leading to novel molecular insights and therapeutic potentials toward glioblastoma multiforme treatment.

3p vimichaelfaraday 25-03-2022 11 1   Download

Molecular knowledge regarding the primary esophageal achalasia is essential for the early diagnosis and treatment of this neurodegenerative motility disorder. Therefore, there is a need to find the main microRNAs (miRNAs) contributing to the mechanisms of achalasia. This study was conducted to determine some patterns of deregulated miRNAs in achalasia. This case-control study was performed on 52 patients with achalasia and 50 nonachalasia controls. The miRNA expression profiling was conducted on the esophageal tissue samples using the next-generation sequencing (NGS).

13p thiencuuchu 27-11-2021 9 2   Download

Understanding of the functions of microRNAs in breast cancer and breast cancer stem cells have been a hope for the development of new molecular targeted therapies. Here, it is aimed to investigate the differences in the expression levels of let-7a, miR10b, miR-21, miR-125b, miR-145, miR-155, miR-200c, miR-221, miR-222 and miR-335, which associated with gene and proteins in MCF-7 (parental) and MCF-7s (Mammosphere/stem cell-enriched population/CD44+/CD24-cells) cells treated with paclitaxel. MCF7s were obtained from parental MCF-7 cells.

12p thiencuuchu 27-11-2021 16 2   Download

Completely and systematic study of taxonomy of the Cashew family (Anacardiaceae) in Vietnam, based on evidence of morphology and molecular biology, as a scientific basis for the compilation of Flora of Vietnam about Anacardiaceae in Vietnam.

27p angicungduoc11 17-04-2021 18 4   Download

The objective of the thesis is to successfully build up a process for preparation of bioactive water-soluble low molecular weight β-glucan product from from spent brewer’ yeast by irradiation method.

31p capheviahe26 25-01-2021 40 5   Download

In this study, 180 gastric biopsies were taken from patients of Hai Duong Provincial General Hospital who had come to the hospital to be treated for gastritis during the period January 2015 to July 2015. All of the subjects were 18-80 years old; they had chronic gastritis, a stomach ulcer or gastric cancer; they did not use antibiotics for 30 days prior to our endoscopy.

6p tamynhan9 02-12-2020 10 1   Download

The basic helix-loop-helix transcription factors play important roles in diverse cellular and molecular processes. Comparative functional genomics can provide powerful approaches to draw inferences about gene function and evolution among species.

21p vishikamaru2711 29-04-2020 15 3   Download

Melon shows a broad diversity in fruit morphology and quality, which is still underexploited in breeding programs. The knowledge of the genetic basis of fruit quality traits is important for identifying new alleles that may be introduced in elite material by highly efficient molecular breeding tools.

17p vishikamaru2711 29-04-2020 19 3   Download

High-molecular-weight glutenin subunits (HMW-GS) play important roles in the elasticity of dough made from wheat. The HMW-GS null line is useful for studying the contribution of HMW-GS to the end-use quality of wheat.

12p vishikamaru2711 29-04-2020 15 1   Download

Rapeseed (Brassica napus L.) and soybean (Glycine max L.) seeds are rich in both protein and oil, which are major sources of biofuels and nutrition. Although the difference in seed oil content between soybean (~ 20%) and rapeseed (~ 40%) exists, little is known about its underlying molecular mechanism.

15p vishikamaru2711 29-04-2020 11 0   Download

The auxin response factor (ARF) gene family is involved in plant development and hormone regulation. Although the ARF gene family has been studied in some plant species, its structural features, molecular evolution, and expression profiling in Brachypodium distachyon L. are still not clear.

15p vishikamaru2711 29-04-2020 31 2   Download

Among various pests, the brown planthopper (BPH) that damages rice is the major destructive pests. Understanding resistance mechanisms is a critical step toward effective control of BPH.

11p vishikamaru2711 29-04-2020 10 0   Download

Objects of research: Appraising of the species diversity and the variation according to space of Chrysomelidae in Nui Chua national park. Determining the food of Chrysomelidae and appraising the change of their food according to space.

25p xacxuoc4321 09-07-2019 35 8   Download

Objectives of the thesis: Identifying the Meloidogyne species causing damage on main crops in Tay Nguyen Highlands. Analyze the diversity of Meloidogyne species based on morphology and molecular classification. Assessing the preventative ability of antagonistic microorganisms to Meloidogyne incognita in laboratory condition.

27p xacxuoc4321 08-07-2019 35 5   Download

In this paper the individual markers (COI and 18S rRNA) were successfully used to identify some sponge taxa at the species level. The obtained results showed the congruence of molecular taxonomy using two independent markers. However, our study showed that a combination of the two markers provided more information and supported better for sponge identification.

10p shiwo_ding7 05-06-2019 32 3   Download

Chapter 1 - A brief history. This chapter introduce to a brief history of molecular biology. Molecular biology grew out of the disciplines of genetics and biochemistry. In this chapter we will review the major early developments in the history of this hybrid discipline, beginning with the earliest genetic experiments performed by Gregor Mendel in the mid-nineteenth century.

22p tangtuy05 30-03-2016 81 3   Download