Nasopharyngeal carcinoma

Ung thư vòm họng là thể ung thư thường gặp nhất trong số các ung thư ở vùng đầu cổ và là một trong mười ung thư phổ biến nhất tại Việt Nam. Bệnh có thể gặp ở mọi lứa tuổi nhưng hay gặp ở nam giới, tuổi từ 20 đến 65. Bài giảng Ung thư vòm Nasopharyngeal carcinoma (NCP) này sẽ giúp bạn nắm được đại cương về bệnh, yếu tố nguy cơ, triệu chứng lâm sàng,...Mời bạn đọc cùng tham khảo.

19p tuoihaimuoi32 19-06-2014 73 12   Download

Objectives: To study fluctuation of plasma cell-free Epstein Barr virus DNA at pre-, mid- and post-radiotherapy of nasopharyngeal carcinoma patients. Methods: 21 nasopharyngeal carcinoma patients of stages I - IVB were followed up and the sensitive realtime PCR assay with detection limit of 25 copies/mL was performed for quantification of plasma cell-free Epstein Barr virus DNA.

7p vixyliton2711 17-04-2019 8 0   Download

DNA hypermethylation changes in CpG islands of promoter region of E-cadherin (E-cad) gene, one of the tumor suppressor genes, have been described to be involved the formation and progression of human nasopharyngeal carcinoma, which is the most common and highly incident cancer of head and neck cancer in Asian countries, especially in Vietnam.

8p vititan2711 14-08-2019 6 0   Download

This study examined the presence of Epstein-Barr virus (EBV) in nasopharyngeal carcinoma (NPC) based on the detection of EBNA-1 (Epstein-Barr virus nuclear antigen-1) by Polymerase Chain Reaction (PCR), in Vietnamese population.

8p vithomasedison2711 14-08-2019 6 0   Download

Nasopharyngeal carcinoma (NPC) is a highly invasive and malignant tumor of the nasopharynx, the uppermost region of the pharynx, gravitating toward Southeast Asia, especially Vietnam. The etiology of NPC is suggested to be involved to several genetic susceptibility and environmental factors. miRNAs (microRNA), the short non-coding RNA molecular, have been reported that played important roles, as oncogene and/or tumor suppressor gene, in progression and development of NPC.

8p vithomasedison2711 14-08-2019 9 0   Download

In Vietnam, nasopharyngeal carcinoma (NPC) is the eighth most common cause of death from cancer. Cell-free Epstein Barr virus DNA (cf-EBV DNA) was reported to be present in almost all NPC patients. However, currently available assays in Vietnam can detect cf-EBV DNA in only 67.6% of NPC patients, thus leaving 32.4% of cancer cases undetected.

7p caygaocaolon1 13-11-2019 4 0   Download

Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, for which radiotherapy and/or chemotherapy are the primary treatment methods. Many herbs are known to have potential uses in chemotherapy; however, the mechanisms underlying the observed antitumor activity of Ajuga bracteosa (AB) against NPC remain unclear.

8p vilusaka2711 19-11-2019 5 0   Download

miRNA (microRNA) are short RNA molecules in length from 20 to 24 nucleotides that have been shown to play an important role in regulating gene expression in many different types of human cancer. Meanwhile, miRNA-214 is one of the known miRNAs involved in the formation of nasopharyngeal carcinoma (NPC) through overexpression that promotes proliferation and development of cancer cells. However, in Vietnam, the study of miR-214 related to NPC has not been conducted yet.

10p chauchaungayxua1 03-12-2019 12 0   Download

Nasopharyngeal carcinoma (NPC) is one of the most frequent cancer types in Vietnam, with high mortality rate. Therefore, the early diagnosis and detection of NPC is urgently needed to improve patient survival. Recent studies have confirmed that the infection of Epstein-Barr virus (EBV) and polymorphism in RPMS1 and A73 are considered as the etiological factor associated with NPC. However, in Vietnam, there are no studies relevant to the identification of polymorphism of RMPS1 and A73.

12p chauchaungayxua1 03-12-2019 27 0   Download

To evaluate the pathological characteristics of nasopharyngeal carcinoma in Hue Central Hospital. This was a retrospective review of all patients seen at Pathology Department, Hue Central Hospital with the diagnosis of nasopharyngeal carcinoma between January 1st 2017 and June 30th, 2018.

3p vistockholm2711 13-12-2019 5 0   Download

Induction chemotherapy (IC) combined with concurrent chemoradiotherapy (CCRT) has been recommended as the first-line therapy for locoregional nasopharyngeal carcinoma (NPC). Due to the different chemotherapeutic drugs used in the IC and CCRT, the results remain controversial.

13p viorochimaru2711 30-05-2020 6 0   Download

Nasopharyngeal carcinoma (NPC), with distinct geographical distribution, has gathered public attention. Despite that radiotherapy and chemotherapy are applied to treat NPC, cell metastasis still cannot be avoided.

10p viorochimaru2711 01-06-2020 1 0   Download

Long noncoding RNAs (lncRNAs) have been reported to be important regulators in pathogenesis of human cancers, including nasopharyngeal carcinoma (NPC). Here, we mainly aimed to explore the mechanisms of LncRNA-SNHG5/ miR-1179/HMGB3 axis in NPC progression.

11p vijakarta2711 09-06-2020 4 0   Download

To determine the optimal timing of the first Magnetic Resonance Imaging (MRI) scan after curativeintent radiotherapy (RT) for nasopharyngeal carcinoma (NPC), and evaluate the role of MRI in surveillance for locoregional recurrence (LRR).

7p vijakarta2711 09-06-2020 4 0   Download

Locally advanced nasopharyngeal carcinoma (LA-NPC) is a relatively rare disease in the west but more common in East Asia and areas of the Middle East like Saudi Arabia. Despite the advances in radiation therapy techniques, some patients relapse after treatment.

13p vijakarta2711 09-06-2020 4 0   Download

Early radiation-induced temporal lobe injury (RTLI) diagnosis in nasopharyngeal carcinoma (NPC) is clinically challenging, and prediction models of RTLI are lacking. Hence, we aimed to develop radiomic models for early detection of RTLI.

9p vikuala271 13-06-2020 7 0   Download

Nimotuzumab (NTZ) is an anti-EGFR monoclonal antibody. However,the effect of targeted drugs combined with induction therapy in locally advanced nasopharyngeal carcinoma remains unclear.

10p vikuala271 13-06-2020 1 0   Download

Intratumoral heterogeneity has an enormous effect on patient treatment and outcome. The purpose of the current study was to establish and validate a nomogram with intratumoral heterogeneity derived from 18Ffluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for prognosis of 5-Year progression-free survival (PFS) of patients with nasopharyngeal carcinoma (NPC).

12p vikuala271 13-06-2020 4 0   Download

Chemoradiotherapy (CRT) with high cumulative doses (CDs) of cisplatin has been considered the standard of care for non-metastatic nasopharyngeal carcinoma (NPC). However, given most patients’ inability to tolerate high CDs due to cisplatin-related toxicities, the optimal CD of cisplatin during CRT remains undetermined.

10p vikuala271 13-06-2020 5 0   Download

To explore prognostic value of the pre-treatment primary lesion apparent diffusion coefficient (ADC) in locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

8p vikuala271 13-06-2020 2 0   Download