Precision medicine

part 2 book “new health technologies - managing access, value and sustainability” has contents: ensuring timely and affordable access to medical devices, achieving the promise of precision medicine, digital technology - making better use of health data.

113p tieu_vu14 15-08-2018 6 0   Download

Shortly before I began research for this book on alternative and complementary medicine, I informed a dear friend of the pending task. His first comment was “How many volumes?” Those three words would haunt me throughout the project. One book hardly scratches the surface; therefore my objectives were to compile up-to-date information on and explanations of as many alternative, complementary, or integrative healing methods as possible and to present them in an unbiased and accessible A-to-Z format.

303p cronus75 18-01-2013 45 9   Download

The Economics of Global Health Political and economic concerns have often guided global health interventions. As mentioned previously, early efforts to control yellow fever were tied to the completion of the Panama Canal. However, the precise nature of the link between economics and health remains a matter for debate. Some economists and demographers argue that economic development is the key to improving the health status of populations, while others maintain that ill health is the chief barrier to development in poor countries.

5p tubreakdance 26-11-2010 60 5   Download

Chapter Two The precise scientific medical rules for cupping 19 operation The place of person's body for applying the 20 cupping operation The suitable age for applying cupping operation Timing of Applying Cupping operation The Relation between the Moon and Cupping The Physiological Condition of the Body.

136p addition1122 26-04-2013 27 2   Download

What attracted us to plastic surgery are its tremendous scope and the multitude of approaches for every clinical situation. Yet precisely these aspects of plastic surgery make its study and teaching especially challenging. Although there are several excellent atlases and texts, we have come across few references that are compact, affordable, timely, and focus on the practical, day-to-day practice of plastic surgery.

620p crazy_sms 09-05-2012 81 21   Download

Internal Medicine is designed to provide the busy clinician with precisely the information needed where and when it is needed. The Associate Editors and contributors are internationally recognized authorities, and they have organized the content specifically so as to convey the essentials necessary for diagnosis, differential diagnosis, management, treatment and follow-up. Many topics start with a “What To Do First” heading which brings the collective experience and guidance of top experts to bear on the “up front” considerations the clinician must face.

1591p hyperion75 21-01-2013 38 9   Download

The SI standard of time is based on: A. the daily rotation of the earth B. the frequency of light emitted by Kr86 C. the yearly revolution of the earth about the sun D. a precision pendulum clock E. none of these Ans: E 2. A nanosecond is: A. 109 s B. 10−9 s C. 10−10 s D. 10−10 s E. 10−12 Ans: B 3. The SI standard of length is based on: A. the distance from the north pole to the equator along a meridian passing through Paris B. wavelength of light emitted by Hg198 C. wavelength of light...

655p gian_anh 18-10-2012 79 8   Download

Medicine and dentistry are continuously evolving, due largely to the influences and interactions of new methods, technologies, and materials. Partly because of outdated testing requirements, our students can no longer adequately meet the increasing demands these changes have placed on a patient-oriented education.

0p hyperion75 21-01-2013 39 7   Download

Classification Approximately 20 different groups of sarcomas are recognized on the basis of the pattern of differentiation toward normal tissue. For example, rhabdomyosarcoma shows evidence of skeletal muscle fibers with cross-striations; leiomyosarcomas contain interlacing fascicles of spindle cells resembling smooth muscle; and liposarcomas contain adipocytes. When precise characterization of the group is not possible, the tumors are called unclassified sarcomas. All of the primary bone sarcomas can also arise from soft tissues (e.g., extraskeletal osteosarcoma).

5p konheokonmummim 03-12-2010 78 6   Download

This effort is the culmination of my lifelong attraction to medical terminology - that which continues to be a source of fulfillment for me. Throughout, I have been impacted by the enhanced efficiency and clarity which is inherent in medical nomenclature. How do nurses view charting? Too often, it is the last load of the shift, in which haste and other demands cloud a precise recall of details.

0p mnemosyne75 02-02-2013 33 5   Download

CONSTIPATION Definition Constipation is a common complaint in clinical practice and usually refers to persistent, difficult, infrequent, or seemingly incomplete defecation. Because of the wide range of normal bowel habits, constipation is difficult to define precisely. Most persons have at least three bowel movements per week; however, low stool frequency alone is not the sole criterion for the diagnosis of constipation.

5p ongxaemnumber1 29-11-2010 43 3   Download

Unequal Crossing-Over Normally, DNA recombination in germ cells occurs with remarkable fidelity to maintain the precise junction sites for the exchanged DNA sequences (Fig. 62-3). However, mispairing of homologous sequences leads to unequal crossover, with gene duplication on one of the chromosomes and gene deletion on the other chromosome. A significant fraction of growth hormone (GH) gene deletions, for example, involve unequal crossing-over (Chap. 333).

5p konheokonmummim 03-12-2010 47 3   Download

Diagnosis is fundamental to the appropriate treatment and wellbeing of the equine patient. Despite the many excellent clinical texts that are available, few seem to explain in sufficiently precise terms which clinicopathological tests are appropriate or how particular techniques should be performed. The first edition of this book was designed to provide an illustrated practical guide to the various diagnostic techniques employed in equine medicine. This second edition is an update by international experts in the field.

0p camchuong_1 10-12-2012 29 3   Download

Prolonged exposure of pancreatic beta cells to the sulfonylureas glibenca-mide and tolbutamide induces subsequent desensitization to the actions of these drugs. The precise mechanisms underlying this desensitization remain unknown, prompting the present study, which investigated the impact of prolonged sulfonylurea exposure on glucose and energy metabolism using clonal pancreatic BRIN-BD11 beta cells.

9p inspiron33 23-03-2013 25 3   Download

Many branchiopod crustaceans are endowed with extracellular, high-molecular-weight hemoglobins whose exact structural characteristics have remained a matter of conjecture. By using a broad spectrum of techniques, we provide precise and coherent information on the hemoglobin of one of the phylogenetically ‘oldest’ extant branchiopods, the tadpole shrimp Triops cancriformis.

17p inspiron33 25-03-2013 26 3   Download

Cadherins belong to a family of homophilic cell–cell adhesion proteins that are responsible for the establishment of a precise cell architecture and tissue integrity. Moreover, experimental data suggest that loss of intercellular adhesion is inversely correlated with cellular differentiation. Furthermore, dedifferentiation is closely linked to tumor progression.

13p galaxyss3 07-03-2013 21 2   Download

Bone morphogenetic proteins (BMPs) are known to be widely involved in various biological processes. Many of the members of the BMP family, as well as related factors, receptors and molecules in the BMP signaling path-way, have been isolated, but their precise functions are still unclear.

8p galaxyss3 19-03-2013 24 2   Download

Human serum albumin (HSA) exists in both reduced and oxidized forms, and the percentage of oxidized albumin increases in several diseases. How-ever, little is known regarding the pathophysiological significance of oxida-tion due to poor characterization of the precise structural and functional properties of oxidized HSA.

12p inspiron33 25-03-2013 27 2   Download

Why do proteins adopt the conformations that they do, and what determines their stabilities? While we have come to some understandingof the forces that underlie protein architecture, a precise, predictive, physicochemical explanation is still elusive. Two obstacles to addressing these questions are the unfathomable vastness of protein sequence space, and the difficulty in makingdirect phy-sical measurements on large numbers of protein variants. Here, we review combinatorial methods that have been applied to problems in protein biophysics over the last 15 years.

14p dell39 03-04-2013 41 2   Download

During DNA replication, transcription and DNA repair in eukaryotes, the cellular machineries performing these tasks need to gain access to the DNA that is packaged into chromatin in the nucleus.Chromatin is a dynamic structure thatmodulates the access of regulatory factors to the genetic material.A precise coordination and organization of events in opening and closing of the chromatin is crucial to ensure that the correct spatial and temporal epigenetic code is maintained within the eukaryotic genome....

15p dell39 03-04-2013 22 2   Download