Systems in c

This qualitative study focuses on identifying the formal and informal performance management (PM) practices currently in use in Australian public universities for academic staff Levels A, B and C.

325p runthenight04 02-02-2023 5 2   Download

The purpose of this study is to expand the understanding of IT student retention in Taiwan. Three objectives are proposed: (a) to identify at-risk students who are most likely to drop out; (b) to model Information System (IS) student retention; and (c) to inform intervention programs for at-risk students. The significance of this study is in serving to better inform faculties, staff and administrators of higher education institutions in turn to help strengthen the retention of IT students.

309p runthenight04 02-02-2023 8 3   Download

This research aims to develop novel approaches capable for effectively solving the IS project evaluation and selection problem in a simple and straightforward manner. More specifically, this research will: (a) Conduct a comprehensive review of existing approaches to evaluating and selecting IS projects; (b) Develop novel approaches for evaluating and selecting IS projects; and (c) Demonstrate the applicability of the developments in real IS project evaluation and selection situations with real world applications.

154p runthenight04 02-02-2023 5 2   Download

Research is conducted on the Ban Pig model with goals: To determine the potential of Ban Pig's oocyte exploitation; to determine cultivate conditions of the oocyte mature in Ban Pig; success in establishing create Pig’s embryo system through in vitro fertilization (IVF) and cloning (C).

28p beloveinhouse01 15-08-2021 14 3   Download

The main goal of this paper is to: 1) presents ITSs used in the STEM+C education; and 2) introduce data-driven ITSs for STEM+C education.

9p lucastanguyen 01-06-2020 14 1   Download

This article shows how the most recent gadolinium cross sections evaluations appear inadequate to provide accurate criticality calculations for a system with gadolinium fuel pins. In this article, a sensitivity and uncertainty analysis (S/U) has been performed to investigate the effect of gadolinium odd isotopes nuclear cross sections data on the multiplication factor of some LWR fuel assemblies.

11p christabelhuynh 30-05-2020 16 2   Download

The paper discusses scientific challenges faced in the beginning and achievements made throughout the projects, including the industrial impact and lessons learned.

6p christabelhuynh 29-05-2020 19 1   Download

A novel vector platform for vitamin H-inducible transgene expression in mammalian cells have therefore designed a strategy to convert antibiotic-responsive transcription factors into gene regulation systems responsive to non-toxic biotin, also known as vitamin H.

9p thuyancn 01-06-2015 43 5   Download

The present work describes an experimental study on sewage sludge pyrolysis in a Fluidised Bed Reactor(FluBR) and the effect on the pyrolysis liquid product of passing the hot exhaust (pyrolysis) vapours through a Fixed Bed Reactor (FixBR) filled with gamma-alumina (c-Al2O3).

9p tuananhhumg 04-11-2013 49 3   Download

Recent years have witnessed high levels of activity in identifying enzyme systems that catalyse H-transfer by quantum tunneling. Rather than being restricted to a small number of specific enzymes as perceived initially, it has now become an accepted mechanism for H-transfer in a growing number of enzymes. Furthermore, H-tunneling is driven by the thermally induced dynamics of the enzyme. In some of those enzymes that break stable C–H bonds the reaction proceeds purely by quantum tunneling, without the need to partially ascend the barrier.

7p system191 01-06-2013 40 3   Download

To examine the role of the distal His42 residue in the catalytic mechanism of pea cytosolic ascorbate peroxidase, two site-directed variants were prepared in which His42 was replaced with alanine (H42A) or glutamic acid (H42E). Electronic spectra of the ferric derivatives of H42A and H42E (pH 7.0, l ¼ 0.10 M, 25.0 °C) revealed wavelength maxima [kmax (nm): 397, 509, % 540sh, 644 (H42A); 404, 516, % 538sh, 639 (H42E)] consistent with a predominantly fiveco-ordinate high-spin iron. The specific activity of H42E for oxidation of L-ascorbate (8.2 ± 0.

11p system191 01-06-2013 39 4   Download

The long uORF-burdened 5¢UTRs of many genes encoding regulatory proteins involved in cell growth and differentiation contain internal ribosomal entry site (IRES) elements. In a previous study we showed that utilization of the weak IRES of platelet-derived growth factor (PDGF2) is activated during megakaryocytic differentiation.

10p system191 01-06-2013 34 4   Download

DNA transactions in eukaryotes require that proteins gain access to target sequences packaged in chromatin. Further, interactions between distinct nucleoprotein complexes are often required to generate higher-order structures. Here, we employed two prokaryotic site-specific recombination systems to investigate how chromatin packaging affects the assembly of nucleoprotein structures of different complexities at more than 30 genomic loci. The dynamic nature of chromatin permitted protein–DNA and DNA–DNA interactions for sites of at least 34 bp in length.

7p system191 01-06-2013 50 4   Download

Med. Zentrum fur Hygiene und Medizinische Mikrobiologie, Philipps-Universitat Marburg, Marburg, Germany Mannose analogues (2-deoxy-D -glucose, 2-deoxy-2-fluoroD -glucose and 2-amino-2-deoxy-D -mannose) have been used to study glycosylphosphatidylinositol (GPtdIns) biosynthesis and GPtdIns protein anchoring in protozoal and mammalian systems. The effects of these analogues on GPtdIns biosynthesis and GPtdIns-protein anchoring of the human malaria parasite Plasmodium falciparum were evaluated in this study. ...

8p system191 01-06-2013 28 4   Download

Mice expressing a C-terminal fragment of the prion protein instead of wild-type prion protein die from massive neuronal degeneration within weeks of birth. The C-terminal region of PrPc (PrP121–231) expressed in these mice has an intrinsic neurotoxicity to cultured neurones. Unlike PrPSc, which is not neurotoxic to neurones lacking PrPc expression, PrP121–231 was more neurotoxic to PrPc-deficient cells. Human mutations E200K and F198S were found to enhance toxicity of PrP121–231 to PrP-knockout neurones and E200K enhanced toxicity to wild-type neurones.

10p system191 01-06-2013 31 4   Download

The decoy approach against nuclear factor kB (NF-kB) is a useful tool to alter NF-kB dependent gene expression using synthetic oligonucleotides (ODNs) carrying NF-kB specific cis-elements. Unfortunately, ODNs are not stable and need to be extensively modified to be used in vivo or ex vivo. We have previously evaluated the possible use of peptide nucleic acids (PNAs) as decoy molecules. The backbone of PNAs is composed of N-(2-aminoethyl)glycine units, rendering these molecules resistant to both nucleases and proteases.

10p system191 01-06-2013 42 4   Download

Cytochrome c is widely distributed in bacterial species, from mesophiles to thermophiles, and is one of the best-characterized redox proteins in terms of biogenesis, folding, structure, function, and evolution. Experimental molecular biology techniques (gene cloning and expression) have become applicable to cytochrome c, enabling its engineering and manipulation. Heterologous expression systems for cytochromes c in bacteria, for use in mutagenesis studies, have been established by extensive investigation of the biological process by which the functional structure is formed. ...

7p research12 01-06-2013 32 3   Download

Antizyme is a polyamine-induced cellular protein that binds to ornithine decarboxylase (ODC), and targets it to rapid ubiquitin-independent degradation by the 26S proteasome. However, the metabolic fate of antizyme is not clear. We have tested the stability of antizyme in mammalian cells. In contrast with previous studies demonstrating stability in vitro in a reticulocyte lysate-based degradation system, in cells antizyme is rapidly degraded and this degradation is inhibited by specific proteasome inhibitors. ...

7p research12 01-06-2013 40 3   Download

Interleukin 4 (IL-4) can act on target cells through an IL-4 receptor complex consisting of the IL-4 receptorachain and the commoncchain (cc). An IL-4 epitope forccbinding has previously been identi®ed. In this study, thecc residues involved in IL-4 binding were de®ned by alanine-scanning mutational analysis. The epitope comprisescc residues I100, L102, and Y103 on loop EF1 together with L208 on loop FG2 as the major binding determinants.

10p research12 29-04-2013 27 2   Download

All living organisms contain redox systems involving thior-edoxins (Trx), proteins featuringanextremelyconservedand reactive active site that perform thiol-disul®de interchanges with disul®de bridges of target proteins. In photosynthetic organisms, numerous isoforms of Trx coexist, as revealedby sequencing ofArabidopsisgenome. The speci®c functions of many of them are still unknown.

11p research12 29-04-2013 34 2   Download