Termination of utilities
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In humans, thromboxane (TX) A2 signals through two TXA2receptor (TP) isoforms, TPaand TPb,thatdiverge within their carboxyl terminal cytoplasmic (C) tail regions and arise by differential splicing. The human TP gene con-tains three exons E1–E3; while E1 exclusively encodes 5¢ untranslatedregion (UTR) sequence,E2andE3 represent the main coding exons. An additional noncoding exon, E1b was identified within intron 1. Additionally, the TP gene contains twopromoters P1 andP2 located 5¢of E1 andE1b, respectively....
16p research12 23-04-2013 42 3 Download
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Escherichia colilow molecular mass penicillin-binding pro-teins (PBPs) include PBP4, PBP5, PBP6 and PBP6b. Evi-dence suggests that these proteins interact with the inner membrane via C-terminal amphiphilica-helices. Nonethe-less, the membrane interactive mechanisms utilized by the C-terminal anchors of PBP4 and PBP6b showdifferences to those utilized by PBP5 and PBP6. Here, hydrophobic moment-based analyses have predicted that, in contrast to the PBP4 and PBP6b C-termini, those of PBP5 and PBP6 are candidates to form oblique orientateda-helices....
9p tumor12 22-04-2013 45 3 Download
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Exposure of cells to ionizing radiation induces activation of multiple signal-ing pathways that play a critical role in controlling cell death. However, the basis for linkage between signaling pathways and the cell-death machin-ery in response to ionizing radiation remains unclear.
13p media19 06-03-2013 34 3 Download
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16.1. Terminal The keyhole into Mac OS X's Unix innards is a program called Terminal, which sits in your Applications Utilities folder (see Figure 16-2). Terminal is named after the terminals (computers that consist of only a monitor and keyboard) that still tap into the mainframe computers at some universities and corporations
5p daisuphu 28-07-2010 94 8 Download