Using monoclonal antibodies

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Characterization of Antigenic Sites on the Rinderpest Virus N Protein Using Monoclonal Antibodies

9p hoami_266 16-09-2011 17 2   Download

Twenty-five years ago, Georges Köhler and César Milstein invented a means of cloning individual antibodies, thus opening up the way for tremendous advances in the fields of cell biology and clinical diagnostics (1). However, in spite of their early promise, monoclonal antibodies (MAbs) were largely unsuccessful as therapeutic reagents resulting from insufficient activation of human effector functions and immune reactions against proteins of murine origin.

456p tom_123 15-11-2012 44 7   Download

Recombinant human transcobalamin (TC) was probed with 17 monoclonal antibodies (mAbs), using surface plasmon resonance measurements. These experiments identified five distinct epitope clusters on the surface of holo-TC. Western blot analysis of the CNBr cleavage fragments of TC allowed us to distribute the epitopes between two regions, which spanned either the second quarter of the TC sequence GQLA…TAAM(103–198) or the C-ter-minal peptide LEPA…

12p fptmusic 11-04-2013 17 1   Download

Trading partner Canada has established the Canadian Adaptation and Rural Development (CARD), national and regional adaptation programs that provide assistance to the sector in the area of research, innovation, capturing market opportunities, environmental sustainability, food safety and quality, human resource capacity building and rural development.

60p tieuyeuquai456 08-10-2012 25 6   Download

A Gallup study of over 250,000 sales people and 25,000 sales managers supports our internal findings that the highest performers use a variety of sales approaches and styles. Even within the same company, many different sales approaches are used by these top performers. In fact, if all the top performers were forced to use a single sales style, many of them would cease to be top producers, would get frustrated and quit. Gallup’s conclusion: No one style is best. Gallup’s study supports our consistent findings: The bank must be flexible enough to allow people to...

0p khanhchilam 01-04-2013 25 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA

8p dauphong3 26-12-2011 24 4   Download

In 1930 Ferguson modified the technique and published his series of 280 patients who had prostate needle aspiration biopsy using an 18-gauge needle via the transperineal approach and was able to remove adequate tissue in 78 to 86% of his cases (Ferguson, 1930) (figure 6). The patient was placed in the lithotomy position and local anaesthetic was infiltrated just lateral to the median raphe 1cm anterior to the anus. The index finger of the left hand was introduced into the rectum guiding an 18 gauge needle introduced into the perineum taking care to avoid the rectum and urethra....

546p ti_du_hoang 10-08-2012 34 4   Download

Historically, the Ontario Medical Association (OMA) has taken a strong stand advocating reductions in air pollution in Ontario as an essential means to improve public health. Beginning in 1967, the Ontario Medical Association Council endorsed a program of air pollution control in Ontario which included the establishment of monitoring stations and regulation of emissions from industry and vehicular traffic (15). Shortly thereafter, the government enacted the Air Pollution Control Act encompassing a number of the recommendations from the OMA.

23p saimatkhauroi 01-02-2013 33 4   Download

There are several exemptions in many State laws that leave children unprotected in vehicles. 8 In nearly half of the States, children can ride unsecured if all safety belts are in use. This means that if a vehicle is overcrowded and other occupants are using all of the safety belts, nobody can be cited if children are unbelted. Another common exemption allows parents, guardians, or other adults to “attend to the personal needs of the child.” This exemption permits an adult to carry a child on his or her lap, while the vehicle is in motion, for...

117p nhacchovina 23-03-2013 20 4   Download

Finally, the last design goal for the API is that it should be possible for a library to use the mechanism without fear of conflicts with the main program. This allows 3 party code that uses the API to be linked into the application without conflict. While on the surface this appears to be obvious, several counter examples exist. Within a process, a signal may only have a single sig- nal handler registered, so library code typically can not use signals. X-window applications only allow for a sin- gle event loop.

0p nhacsihuytuan 06-04-2013 20 3   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: The use of crossreactive monoclonal antibodies to characterize the immune system of the water buffalo (Bubalus bubalis)

7p hoami_266 15-09-2011 23 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis...

12p thulanh27 13-12-2011 29 2   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Localization of antigenic sites at the amino-terminus of rinderpest virus N protein using deleted N mutants and monoclonal antibody

7p hoami_266 16-09-2011 24 1   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Use of flow cytometry to develop and characterize a set of monoclonal antibodies specific for rabbit leukocyte differentiation molecules

16p hoami_238 17-09-2011 23 1   Download

Neuropilin (NRP) and plexin (Plex) that are now known to be semaphorin receptors were initially identified as antigens for monoclonal antibodies (MAbs) that bound to particular neuropiles and plexiform layers of the Xenopus tadpole optic tectum, several years before the discovery of semaphorin. The extracellular segment of the NRP protein is a mosaic of 3 functionally different protein motifs that are thought to be involved in molecular and/or cellular interactions, suggesting that NRP serves in a various cell-cell interaction by binding a variety of molecules.

156p hotmoingay 03-01-2013 20 1   Download

In addition to explicitly named Properties, “code” and “id” attributes are special cases. Every entity in the Thésaurus – Concepts, Kinds, Properties, and Roles – has an associated “code” and “id.” These are used as unique identifiers in the Apelon development software, and, as such, are not defined explicitly as Roles or Properties. This required a hard-coded definition of both entities. They were defined as owl:AnnotationProperties, just like other Properties in the Thésaurus, and this allowed them to be attached to all of the definitions in the ontology.

8p taisaokhongthedung 09-01-2013 26 1   Download

Mucin glycoproteins on breast cancer cells carry shortened carbohydrate chains. These partially deglycosylatedmucin 1 (MUC-1) structures are recognized by the monoclonal antibody SM3, which is being tested for its diagnostic utility. We used NMR spectroscopy to analyze the binding mode and thebindingepitopeof peptideandglycopeptideantigens to the SM3 antibody. The pentapeptide PDTRP and the glycopentapeptide PDT(O-a-D-GalNAc)RP are known lig-ands of the monoclonal antibody.

12p research12 29-04-2013 21 1   Download

Traditional herbal medicine has been used since ancient time in many parts of the world where access to formal and modern healthcare is limited. Nepal is not exempt and in mid-hills, mountainous and rural areas of the country where access and services are limited, herbal medicine is the basis of treatment of most illness through traditional knowledge. It is estimated that approximately 90% of the Nepalese people reside in rural areas where access to government health care facil- ities is lacking [30]. These people rely predominantly on traditional herbal medicine.

16p thangbienthai 17-11-2012 22 0   Download

Quality control has an emerging importance in every field of life. Quality control is a process that is used to guarantee a certain level of quality in a product or service. It might include whatever actions a business deems necessary to provide for the control and verification of certain characteristics of a product or service. With the improvement of technology everyday we meet new and complicated devices and methods in different fields. Quality control should be performed in all of those new techniques.

514p crius75 02-01-2013 40 15   Download

In general, the best beers at a competition should be assigned scores in the 40+ range, with real evaluations of the beer identifying some characteristics of the beer that make it non-perfect. A beer receiving a perfect score of 50 must indeed be perfect; it must have absolutely no flaws, exemplify the style as well as or better than the best commercial examples, be perfectly brewery-fresh, and be well- handled and presented. These conditions might not all be under the brewer’s control, so achieving a perfect beer at the point of presentation to judges is extremely rare. ...

264p conduongdinhmenh 07-05-2013 24 11   Download