Báo cáo khoa học: Perturbation of membranes by the amyloid b-peptide – a molecular dynamics study

The etiology of Alzheimer’s disease is considered to be linked to interac-tions between amyloid b-peptide (Ab) and neural cell membranes. Mem-brane disruption and increased ion conductance have been observed in vitro in the presence of Ab, and it is assumed that these same phenom-ena occur in the brain of an individual afflicted with Alzheimer’s.