Administering

As science and technology has developed, the manner by which drugs can be delivered has grown. Medicines may be taken orally, applied as topical pastes, creams or oils, patches or administered by direct injection to the body. This research explores an alternative method for the delivery of therapeutic compounds to the body. The basis of the study involves the application of traditional medicinal compounds used to cure minor neck and back pains through transdermal topical application, using a textile substrate as the carrier.

128p runthenight07 01-03-2023 10 3   Download

The nasal route for drug administration has the potential for local and systemic delivery of a wide variety of therapeutics. Nasal spray drug delivery has the potential to administer drugs to the bloodstream, avoiding the use of painful needles. While there is great potential, studies in the area are limited and somewhat conflicting. This study aimed to support the improvement of nasal drug delivery through experimental work on a model nasal cavity and through experimental characterisation of nasal spray behaviour. Four different brands of nasal spray were investigated.

91p runthenight04 02-02-2023 8 3   Download

The nasal route for drug administration has the potential for local and systemic delivery of a wide variety of therapeutics. Nasal spray drug delivery has the potential to administer drugs to the bloodstream, avoiding the use of painful needles. While there is great potential, studies in the area are limited and somewhat conflicting. The thesis "Experimental Studies in Aid of Improving Nasal Drug Delivery" aimed to support the improvement of nasal drug delivery through experimental work on a model nasal cavity and through experimental characterisation of nasal spray behaviour.

91p runordie3 06-07-2022 5 3   Download

An experiment was conducted to generate a broad genetic variability through induced mutation using physical and chemical mutagens. Three doses each of gamma rays (20, 40 and 60kR), ethyl methane sulphonate (0.2, 0.4 and 0.6%), nitrosoguanidine (0.005, 0.010, and 0.015%), maleic hydrazide (0.01, 0.02 and 0.03%) and their combinations were administered to the seed of two greengram varieties, Sujata and OBGG-52.

13p angicungduoc6 22-07-2020 21 3   Download

This paper examines the effects of etiquette and unethical behaviour on employee commitment and productivity in India. A descriptive survey research method was adopted for the study using 100 questionnaires, which were administered on Employees in different sectors in India.

7p guineverehuynh 19-06-2020 13 1   Download

Development of optimized pediatric formulations for oral administration can be challenging, time consuming, and financially intensive process. Since its inception, the biopharmaceutical classification system (BCS) has facilitated the development of oral drug formulations destined for adults. At least theoretically, the BCS principles are applied also to pediatrics. A comprehensive age-appropriate BCS has not been fully developed.

9p caothientrangnguyen 09-05-2020 36 3   Download

AR-42, a new orally bioavailable, potent, hydroxamate-tethered phenylbutyrate class I/IIB histone deacetylase inhibitor currently is under evaluation in phase 1 and 2 clinical trials and has demonstrated activity in both hematologic and solid tumor malignancies. This report focuses on the preclinical characterization of the pharmacokinetics of AR-42 in mice and rats.

9p caothientrangnguyen 09-05-2020 18 3   Download

The primary research carried out in this thesis consists of two questionnaires administered online, the first directed at Brazilians living in Ireland and the second directed at potential Irish visitors to Brazil. These surveys investigate the demand, interest, price range and possible destination airports for a direct air service between Brazil and Ireland. Based on the first survey of three hundred Brazilians who are resident in Ireland and the second survey of fifty-two Irish potential visitors to Brazil, price ranges for the flight service from both categories are obtained.

94p nguyenyenyn117 18-06-2019 47 6   Download

Lipopolysaccharide (LPS) from the outer membrane of Gram-negative bac-teria belongs to the most potent activators of the mammalian immune sys-tem. Its lipid moiety, lipid A, the ‘endotoxic principle’ of LPS, carries two negatively charged phosphate groups and six acyl chain residues in a defined asymmetric distribution (corresponding to synthetic compound 506). Tetraacyl lipid A (precursor IVa or synthetic 406), which lacks the two hydroxylated acyl chains, is agonistically completely inactive, but is a strong antagonist to bioactive LPS when administered to the cells before LPS addition. .

14p awards 05-04-2013 28 2   Download

Human serum albumin (HSA) has an extraordinary ligand-binding capac-ity, and transports Fe(III)heme and medium- and long-chain fatty acids. In human immunodeficiency virus-infected patients the administered drugs bind to HSA and act as allosteric effectors. Here, the binding of Fe(III)-heme to HSA in the presence of three representative anti-HIV drugs and myristate is investigated.

12p media19 04-03-2013 42 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Interviewer versus self-administered healthrelated quality of life questionnaires - Does it matter?

11p panasonic05 23-12-2011 50 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery

6p panasonic05 22-12-2011 79 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial

10p thulanh29 18-12-2011 46 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: CpG increases vaccine antigen-specific cell-mediated immunity when administered with hepatitis B vaccine in HIV infection...

7p thulanh28 14-12-2011 60 5   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Biodistribution and blood clearance of plasmid DNA administered in arginine peptide complexes

0p toshiba20 12-11-2011 46 6   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients...

8p coxanh_3 27-10-2011 32 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Impact on respiratory tract infections of heptavalent pneumococcal conjugate vaccine administered at 3, 5 and 11 months of age...

9p toshiba12 21-10-2011 41 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis...

9p thulanh16 21-10-2011 34 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered...

8p toshiba11 20-10-2011 57 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Development and validation of the self-administered Fibromyalgia Assessment Status: a disease-specific composite measure for evaluating treatment effect...

12p thulanh15 18-10-2011 41 3   Download