Administering

In this study, alkyl hydroperoxide reductase (AhpC) from M. bovis was evaluated as a new candidate vaccine antigen against TB in BALB/c mice model. The ahpC gene was amplified from M.bovis genome, cloned, and expressed in Escherichia coli. Vaccine antigen AhpC was formulated with Montanide ISA 61 VG, an oil-based emulsion adjuvant. Both IgG and IL-12 responses were observed in mice after administering the formulation both as a subunit vaccine alone and also as a booster vaccine for BCG immunization.

14p lyhuyenthu 31-01-2023 3 1   Download

In study "Melatonin ameliorates cisplatin-induced neurodegeneration in medulla oblongata through the expressions of Aqp-1,-4, inflammation, and apoptosis pathway genes", the neuroprotective effects of melatonin (MEL) with changes in apoptosis, inflammation, and histopathological morphology were evaluated in the medulla oblongata of cisplatin (CIS) administered rats. Although the side effects of CIS are known in many tissues, its reaction on the medulla oblongata and the molecular association underlying this effect is unclear.

11p lyhuyenthu 31-01-2023 1 1   Download

This study aimed to explore whether EX acts on PD in mice mode. Mice were administered 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine (MPTP) and subjected to a 4-week physical exercise regimen (EX-PD group) and underwent RNA-Seq. Here, MPTP caused PD, which was characterized by neuron shrinkage and behavioral deficits, whereas EX improved PD by rescuing neuronal survival and motor function in mice.

17p lyhuyenthu 31-01-2023 1 1   Download

Hyaluronic acid (HA) is a ubiquitous polysaccharide with diverse biological functions. Is known that in the intestinal epithelium, the exogenous HA of molar mass ≥105 Da orally administered antagonizes TLR4 overexpression resulting from dysbiosis and promotes immunomodulation in multifactorial crosstalk, thus helping to treat or to prevent injuries.

11p vihermione 06-01-2023 8 1   Download

This present research seeks to clarify the learners’ difficulties when acquiring legal English vocabulary at this institution. In order to achieve the aim, survey questionnaires were administered to 165 students of the International Trade and Business Law.

9p viharry 15-12-2022 13 1   Download

The aims of the current study were to examine the social context of naloxone access in three different states (Connecticut, Kentucky, Wisconsin) from the perspectives of key informants (first responders, harm reduction personnel, and pharmacists), who play some role in dispensing or administering naloxone within their communities.

13p viferrari 28-11-2022 4 1   Download

With the advancement of diagnostic modalities, there is an increase in the number of individuals detected with thyroid nodules. There are multiple treatment options for the management of nontoxic benign nodular goiter. Radioactive iodine results in effective goiter size reduction which can be administered as out-patient basis and is an appropriate alternative for patients with higher risk for surgery.

7p viporsche 28-10-2022 3 1   Download

The nasal route for drug administration has the potential for local and systemic delivery of a wide variety of therapeutics. Nasal spray drug delivery has the potential to administer drugs to the bloodstream, avoiding the use of painful needles. While there is great potential, studies in the area are limited and somewhat conflicting. The thesis "Experimental Studies in Aid of Improving Nasal Drug Delivery" aimed to support the improvement of nasal drug delivery through experimental work on a model nasal cavity and through experimental characterisation of nasal spray behaviour.

91p runordie3 06-07-2022 1 0   Download

Both modified FOLFIRINOX (mFFX) and gemcitabine/nab-paclitaxel chemotherapy regimens have been shown to improve clinical outcomes in patients with pancreatic cancer, and are often used interchangeably as the standard of care.

11p viangelamerkel 27-07-2022 5 1   Download

In women with newly diagnosed ovarian cancer, bevacizumab and poly (ADP-ribose) polymerase inhibitors (PARPi) exhibit improved progression-free survival (PFS) when administered concurrent with chemotherapy and/or maintenance therapy, but no study has directly compared their effects.

10p viangelamerkel 27-07-2022 2 1   Download

"CompTIA® Security+: Security+ Guide to Network Security Fundamentals (Sixth edition)" is designed to equip learners with the knowledge and skills needed to be information security professionals. Part 1 of book provide students with knowledge about: introduction to security; malware and social engineering attacks; basic cryptography; advanced cryptography and pki; networking and server attacks; network security devices, design, and technology; administering a secure network; wireless network security;...

398p britaikridanik 05-07-2022 20 2   Download

The study "An Investigation of Factors Influencing the Implementation of GAP among Fruit Farmers in Rayong Province, Thailand" aimed to investigate the current GAP implementation of fruit farmers, and to identify factors affecting such GAP implementation. A series of surveys were conducted in Rayong province by using structured questionnaires which were administered to 258 fruit farmers.

13p ngoccthanh 30-06-2022 8 1   Download

Triple-negative breast cancer (TNBC) constitutes 10–20% of breast cancers and is challenging to treat due to a lack of effective targeted therapies. Previous studies in TNBC cell lines showed in vitro growth inhibition when JQ1 or GSK2801 were administered alone, and enhanced activity when co-administered.

21p visusanwojcicki 28-06-2022 4 1   Download

Endometrial cancer (EC) is a common gynecologic malignancy and patients with advanced and recurrent EC have a poor prognosis. Although chemotherapy is administered for those patients, the efficacy of current chemotherapy is limited. Therefore, it is necessary to develop novel therapeutic agents for EC.

12p visusanwojcicki 28-06-2022 3 1   Download

This research set its sight to leave no stone unturned on the relationship between implementation of public sector scorecard (IPSS) and PBB, and through mediating role of organaizational culture characteristics (OCC). The hypothesized framework which expounded the influence of IPSS on PBB through above stated mediator was empirically proved out utilizing a questionnaire-based survey established and administered to a variety of regions in the South Vietnam.

15p alucardhellsing 04-05-2022 8 1   Download

In infants, sevoflurane is commonly used for induction of anesthesia, following which a muscle relaxant is administered to facilitate tracheal intubation. When rocuronium is used as the muscle relaxant, intubation may be performed before reaching an adequate depth of anesthesia because of its rapid onset.

7p viisaacnewton 25-04-2022 7 1   Download

Etomidate is a commonly used sedative in intravenous anesthesia. The aim of this study was to compare the effects of various etomidate doses administered by continuous infusion on adrenal function in dogs under general anesthesia.

6p viisaacnewton 25-04-2022 3 1   Download

Studies have shown that abdominal girth and vertebral column length have high predictive value for spinal spread after administering a dose of plain bupivacaine. we designed a study to identify the specific correlations between abdominal girth, vertebral column length and a 0.5 % dosage of plain bupivacaine, which should provide a minimum upper block level (T12) and a suitable upper block level (T10) for lower limb surgeries.

6p viisaacnewton 25-04-2022 7 1   Download

Propofol and fentanyl are the most widely administered anesthesia maintaining drugs during colonoscopy. In this study, we determined the median effective concentration (EC50) of propofol required for colonoscopy in elderly patients, and the purpose of this study was to describe the pharmacodynamic interaction between fentanyl and propofol when used in combination for colonoscopy in elderly patients.

5p viisaacnewton 25-04-2022 14 1   Download

Ultrasound guided costotransverse block (CTB) is a relatively new “peri-paravertebral” block that has been described recently. It has been previously reported that CTB, administered with a single high-volume injection, provides effect analgesia in breast conserving surgery. In this study we evaluated the effect of CTB when used in breast cancer surgery.

7p viisaacnewton 26-04-2022 8 1   Download