Thuốc ức chế P2Y12 trong
NMCT cấp có ST chênh lên:
từ khuyến cáo đến thực hành
PGS TS Trương Quang Bình
ĐHYD TP HCM
Söï hoaït hoùa vaø keát taäp tieåu caàu
Yeáu toá moâ vaø söï hoaït hoùa ñöôøng
ñoâng maùu ngoaïi sinh
2 cô cheá chính hình thaønh
huyeát khoái trong NMCT cấp
Collagen
Thrombin
TXA2
Acetylsalicylic acid
ADP
(Fibrinogen
Receptor)
Ức chế P2Y12
TXA2
ADP
ADP
Gp IIb/IIIa Hoaït hoùa
ADP = adenosine diphosphate, TXA2 = thromboxane A2, COX = cyclooxygenase.
Schafer AI. Am J Med. 1996;101:199–209.
Các thuốc kháng tiểu cầu
ESC 2011: P2Y12 inhibitors
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