Báo cáo khoa học: Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis

Eukaryotic translation initiation factor 5A (eIF5A) is a protein that is highly conserved and essential for cell viability. This factor is the only pro-tein known to contain the unique and essential amino acid residue hypu-sine. This work focused on the structural and functional characterization ofSaccharomyces cerevisiaeeIF5A.