Breast cancer

Summary of tumor-produced circulating proteins as biomarkers in breast cancer (BC) detection. Subjects and method: A meta-analysis of 50 researches on protein biomarkers in BC diagnosis.

6p vipanly 28-10-2024 0 0   Download

A novel series of s-triazine derivatives was designed and screened for in silico an cancer activity in histone deacetylase 6 (HDAC6) target by molecular docking method using AutoDock Vina.

10p vifilm 11-10-2024 1 0   Download

Ung thư vú (Breast cancer) được đánh giá là loại ung thư phổ biến nhất, nguyên nhân hàng đầu gây tử vong và trầm cảm ở nữ giới. Việc chẩn đoán sớm và tầm soát luôn được xem trọng như một chiến lược ưu tiên ban đầu, góp phần tăng tỉ lệ sống sót và đáp ứng điều trị tốt ở các bệnh nhân. Một số dấu ấn sinh học lưu thông trong huyết thanh như miRNA, lncRNA đã được đánh giá là tiềm năng cao trong việc phát triển các công cụ chẩn đoán lâm sàng dựa trên biểu hiện.

7p gaupanda051 13-09-2024 4 0   Download

Breast cancer is the most frequently diagnosed cancer and also the leading cause of cancer death in women all over the world. This makes breast cancer a global burden to women health including Vietnam.

5p vinatisu 29-08-2024 1 0   Download

Appendiceal cancer is a very rare disease. Based on 6 cases of appendiceal cancer who were admitted to the Internal Medicine of Breast, Gastroenterology, Hepatology, Urology, Department, Oncology Hospital of Ho Chi Minh City from September 2019 to March 2021, we evaluate the available literature review about diagnosis and treatment of appendiceal cancer.

4p vinatisu 29-08-2024 2 0   Download

To describe the characteristics of patients with HER2-positive breast cancer and to identify the proportion of patients using anti-HER2 therapy, and treatment-making related factors. An analytical cross-sectional study was conducted on 79 patients with BC and HER2-positive diagnosed by immunohistochemistry (IHC) or with FISH at the Oncology Department of Hue University of Medicine and Pharmacy Hospital and Oncology Center of Hue Central Hospital from 1/2021 to 12/2022.

8p vinatisu 29-08-2024 1 0   Download

Depression and anxiety are common problems of cancer patients. They affect importantly the patients’ health, the decision to be treated, and the outcome of the treatment. This study aimed to assess the prevalence of depression and anxiety among cancer patients being treated at Hue University Hospital in 2019 and to reveal its correlation factors.

6p vinatisu 29-08-2024 6 0   Download

The metronomic concept emerged more than 20 year sago, however, a significant development in various solidtumors was noticed in the past 10 years. There are potentially several mechanisms of action against tumor cells including inhibition of angiogenesis. This study aims to assess the efficacy and the safety of ametronomic schedule of oral Vinorelbine (Navelbine) in treatment of metastatic breast cancer.

6p vinatisu 29-08-2024 1 0   Download

Breast cancer is the most commonly diagnosed malignancy and the leading cause of death among women worldwide. The incidence of breast cancer is on the rise in developing countries. Breast cancer patients not only experience physical pain from treatment but may also face mental crises, impaired social function, and impaired quality of life.

9p vinatisu 29-08-2024 4 0   Download

Secondary upper limb lymphedema is a common complication after breast cancer treatment. Among the treatment methods, conservative treatment with complex decongestive therapy brings positive results to patients and it is non - invasive.

6p vinatisu 29-08-2024 1 1   Download

The study aimed to determine the incidence and severity of postoperative complications in early breast cancer (BC) females undergoing immediate breast reconstruction (IBR) with implant and polypropylene mesh (PPM) after nipple-sparing mastectomy (NSM).

8p vinatisu 23-08-2024 1 1   Download

Nghiên cứu này nhằm xác định tỷ lệ lympho bào xâm nhập u (Tumor infiltrating lymphocytes-TILs) và đối chiếu với một số đặc điểm mô bệnh học của ung thư biểu mô vú bộ ba âm tính (Triple-negative breast cancer-TNBC).

9p vinatisu 23-08-2024 2 1   Download

Nghiên cứu "Attention Smooth GAN: Một mô hình chuyển đổi ảnh Mô IHC từ ảnh HE" đề xuất mô hình học sâu có tên là Attention Smooth GAN chuyển đổi ảnh mô vú HE sang IHC nhằm hỗ trợ bác sỹ phát hiện sớm sự phát triển bất thường của các protetin và cung cấp thông tin chi tiết về biểu hiện protein qua đó giúp chẩn đoán bệnh, kết quả này có thể sử dụng để lập phác đồ điều trị cho bệnh nhân. Mời các bạn cùng tham khảo!

11p tuongtrihoai 23-07-2024 6 2   Download

Human epidermal growth factor receptor 2 (HER2) has been identified as a molecular target for breast cancer therapy, such as Trastuzumab (Herceptin®). This has been shown to improve patient survival substantially.

10p vibego 02-02-2024 6 0   Download

Studies on nanoparticle-protein interaction have also not been studied. This would give information on ratio influence on the structural alteration of EGCg in EGCg-AuNPs and its functionality in vivo. Herein, the optimisation of EGCg-AuNPs will be determined with a large pool of stoichiometric synthesises of gold and EGCg. These optimised EGCg-AuNPs would then be studied with bovine serum albumin (BSA) for protein interactions, binding and thermodynamics.

177p runthenight07 01-03-2023 6 3   Download

The research project deals with two different types of data for two separate analysis. The first analysis deals with normalised RNA-seq breast cancer data where machine learning techniques are used to classify and identify the biomarker of cancer. Second analysis deals with raw DNA methylated leukemia samples to determine the mutations.

102p runthenight04 02-02-2023 5 3   Download

The purpose of this phase II study was to evaluate the feasibility of hypofractionated radiotherapy (HFRT) with a dose of 36.5Gy in 10 fractions in postmastectomy patients. From March 2014 to December 2015, 85 patients with locally advanced breast cancer were eligible to participate in this study with a schedule of 36.5Gy in 10 fractions.

8p vielonmusk 21-01-2022 11 1   Download

Breast cancer screening is currently predominantly based on mammography, tainted with the occurrence of both false positivity and false negativity, urging for innovative strategies, as effective detection of early-stage breast cancer bears the potential to reduce mortality.

9p vielonmusk 21-01-2022 37 1   Download

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop better therapeutic approaches. microRNAs’ ability to regulate multiple targets could hold a promising discovery approach to pathways relevant for TNBC aggressiveness.

19p vielonmusk 21-01-2022 12 0   Download

Pegylated liposomal doxorubicin (PLD) is an improved formulation of doxorubicin with comparable effectiveness but significantly lower cardiotoxicity than conventional anthracycline. This study aimed to evaluate the real-world effectiveness and safety of PLD versus epirubicin as neoadjuvant or adjuvant treatment for breast cancer.

11p vielonmusk 21-01-2022 13 1   Download