Đánh giá hiệu quả sử dụng kháng sinh dự phòng trong mổ lấy thai chủ động tại Bệnh viện Sản Nhi Bắc Giang

Post-surgical infections, particularly postoperative infections following cesarean sections, pose a significant challenge in obstetric care, leading to extended hospital stays, increased treatment costs, and potential severe complications. To mitigate these risks, the judicious application of preventative measures, including prophylactic antibiotics, has become an essential component of surgical protocols. This study addresses the critical need to understand the efficacy and factors associated with such interventions in elective procedures. Specifically, this research evaluates the success rate of prophylactic antibiotic therapy in elective cesarean sections and identifies related factors at the Bac Giang Obstetrics and Pediatrics Hospital, aiming to contribute valuable insights into optimizing patient outcomes and healthcare resource management.

Obstetricians, gynecologists, surgeons, infectious disease specialists, hospital administrators, healthcare policymakers, and medical researchers interested in surgical site infection prevention and maternal health.

This study conducted a cross-sectional descriptive analysis at the Bac Giang Obstetrics and Pediatrics Hospital to evaluate the effectiveness of prophylactic antibiotic therapy in elective cesarean sections and identify associated factors. The research involved 3188 patients who received prophylactic antibiotics, with data analyzed using SPSS 20.0 software. The findings revealed an exceptionally high success rate of 99.94% in preventing postoperative infections, indicating the robust efficacy of the chosen antibiotic regimens. All types of antibiotics administered postoperatively were successfully used as prophylactic agents. Further analysis demonstrated that patient characteristics such as age, weight, the specific indication for the C-section (e.g., previous uterine scar, placenta previa, multiple pregnancy), and the type of incision did not significantly compromise the high success rate of the prophylactic treatment. Even in cases of early membrane rupture, a condition often associated with increased infection risk, the prophylactic antibiotics proved effective, showing 100% success in such cases. This highlights the broad applicability and reliability of prophylactic regimens across various patient profiles and clinical scenarios. The implications are substantial: the consistent and effective use of prophylactic antibiotics in elective cesarean sections is paramount not only for ensuring patient well-being but also for reducing healthcare costs and optimizing human resources. The study strongly recommends administering prophylactic antibiotics to all eligible patients undergoing elective C-sections, including those with early membrane rupture. Emphasis is also placed on adherence to sterile surgical techniques and thorough vaginal antisepsis before and after the procedure. This comprehensive approach is vital for maintaining low infection rates and enhancing overall maternal care at the Bac Giang Obstetrics and Pediatrics Hospital and similar medical facilities.