Tác dụng của viên nang cứng An Thần Bà Giằng trên người bệnh mất ngủ không thực tổn

Insomnia is a prevalent sleep disorder significantly impacting physical and mental health, as well as overall quality of life. Globally, and particularly in Vietnam, a substantial portion of the adult population suffers from non-organic insomnia. While modern medicine offers treatments like sleep hygiene, cognitive-behavioral therapy, and pharmaceuticals, these often address symptoms, carry risks of dependence, cognitive impairment, and withdrawal symptoms. Traditional medicine, rooted in ancient practices like acupuncture and herbal remedies, presents a promising alternative. An than Ba Giang hard capsule, a traditional herbal formulation, has shown safety in preclinical studies, yet comprehensive clinical research on its efficacy for non-organic insomnia remains limited. This study addresses this gap by clinically evaluating its therapeutic effects.

Researchers and clinicians specializing in traditional medicine, neurology, sleep disorders, and pharmacology; pharmacists; and healthcare policymakers interested in herbal remedies for non-organic insomnia.

This clinical intervention study aimed to evaluate the therapeutic efficacy of An than Ba Giang hard capsules in patients diagnosed with non-organic insomnia, specifically those classified with a Heart-Spleen deficiency pattern according to traditional medicine. The research involved 52 patients at Vinh Phuc Traditional Medicine Hospital, who received An than Ba Giang at a dose of 6 capsules/day for 30 consecutive days. Key outcomes measured included sleep duration, sleep efficiency, and the Insomnia Severity Index (ISI) scale. Results demonstrated significant improvements across all measured parameters after the 30-day treatment period. Mean sleep duration notably increased from 3.42 ± 0.54 hours to 4.93 ± 0.46 hours (p < 0.01), and sleep efficiency improved from 42.69 ± 6.80% to 77.63 ± 6.37% (p < 0.01). The mean ISI score decreased significantly from 21.15 ± 3.49 to 12.04 ± 3.30 (p < 0.05). Clinically, 36.5% of patients no longer met the criteria for insomnia, while 57.7% were classified as having subthreshold insomnia, with no severe cases remaining. These findings suggest that An than Ba Giang hard capsule possesses significant efficacy in improving non-organic insomnia. The efficacy of An than Ba Giang can be attributed to its herbal components, such as Ziziphi spinosae, Passiflora foetida, and Nelumbo nucifera, which modulate GABA receptors, enhance inhibitory neurotransmission, and exert anxiolytic effects, aligning with both modern pharmacological understanding and traditional medicine principles of nourishing the heart and spleen. This study underscores the potential of traditional medicine in providing a safe and effective treatment option, particularly where conventional therapies may have limitations or side effects, contributing to improved sleep quality and overall patient well-being.