The incidence of stroke in young people is high, but most of the research done has focused on complications of stroke and stroke therapies, but there are no studies looking for genes and mutations of these genes related to stroke in Vietnam. This study aims to identify of CYP4F2*3 variant polymorphism and risk factors in stroke patients at ThaiNguyen National Hospital.

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most predominant agents that cause nosocomial infections. Objectives: To determine the rate of MRSA and the molecular characteristics of the coagulase encoding gene of these isolates based on polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP).

Lecture Java programming language: Inheritance and Polymorphism has main content such as Object-Oriented programming, extending a class, implementing a subclass, polymorphism, abstract classes, interfaces.

Determining the frequency of genotype and allele of TNF-α – 308 and TGF-β1-509 in HCC patients with HBsAg (+). Analysing the association of TNF-α-308, TGF-β1-509 polymorphism with risk of HCC and some clinical and subclinical characteristics of HCC patients.

Assessment of genotype diversity was studied using released and in pipeline genotypes of wheat, of these 22 were released and 14 were in pipeline . Genetic diversity among 36 wheat genotypes was studied using Random amplified polymorphic DNA (RAPD) analysis. 21 RAPD primers (RPI primers) were used for screening 36 wheat genotypes from which 2,868 fragments were amplified. It was observed that 63.3% bands were polymorphic and 36.4% were monomorphic. The percent of polymorphic bands in banding pattern was calculated and it was highest in RPI-22 (81.3%) while lowest was recorded in RPI-2 (33.8%) and highest PIC value was observed in RPI-22 and RPI-25 (0.88) while lowest in RPI-7 (0.70). Maximum fragments were produced in RPI-1 (200) and minimum in RPI-7 (82).

Single-nucleotide polymorphisms (SNP) are common genetic changes in the human genome. In recent time, many scientists have shown their interests in studies on SNPs’ roles in the pathological risk especially in cancer and metabolic diseases.

To assess the frequency allele and genotypic distribution of polymorphism rs165599 in catechol-O-methyltransferase in Kinh ethnic-patients with schizophrenia. Subjects and methods: A case-control study consisted of 227 schizophrenic patients and 92 healthy controls in the Kinh ethnic. The rs165599 was genotyped by PCR-RFLP and statistical analysis was performed by Chi-Square test. Results: The frequency of allele A and G in schizophrenic patients were 72.36% and 69.94%, respectively. The frequency of allele A and G in healthy controls were 27.64% and 30.06%, respectively (p > 0.05). In terms of distribution of AA genotype, the rate was 78.75% (patients) and 21.25% (controls). In terms of distribution of AG and GG genotype in schizophrenic patients and healthy controls were respectively: AG (66.05%, 33.95%); GG (74.03%, 25.97%) (p > 0.05). Conclusion: There was no correlation among the frequency of allele, genotypic distribution of polymorphism rs165599 and schizophrenia in the Kinh ethnic.

Dưới đây là bài giảng Lập trình trên Windows với Microsoft® .NET: Bài 5 do Hồ Hoàn Kiếm biên soạn. Mời các bạn tham khảo bài giảng để hiểu rõ hơn về kế thừa trong C#; Overriding Method; tính đa hình - Polymorphism; lớp trừu tượng – Abstract Class; giao diện – Interface.

Bài giảng Lập trình hướng đối tượng: Virtual method và Polymorphism trình bày các nội dung chính như: Nối kết tĩnh (Static binding), nối kết động (Dynamic binding), chạy chương trình, bài toán thực tế, phương thức ảo,...và một số nội dung khác

Báo cáo Kỹ thuật di truyền: Kỹ thuật Aflp (amplified fragments length polymorphism) sẽ giới thiệu về kỹ thuật Aflp; nguyên tắc, hóa chất, trang thiết bị, dụng cụ; các bước tiến hành; ưu, nhược điểm; ứng dụng; kết luận và tài liệu tham khảo.

Phương thức của lớp cha khi thực hiện sẽ được thay thế bằng một phương thức của lớp con thì .phương thức này gọi là có tính đa hình. Tính đa hình giúp cho việc lập trình đơn giản và dễ mở rộng. .Để cài đặt phương thức có tính đa hình ta dùng phương thức ảo và phương thức thuần ảo.

The HIV-1 proteinase (PR) has proved to be a good target for antiretroviral therapy of AIDS, and various PR inhibi-tors are now in clinical use. However, there is a rapid selec-tionof viral variantsbearingmutations in theproteinase that are resistant to clinical inhibitors. Drug resistance also involves mutations of the nucleocapsid/p1 and p1/p6 clea-vage sites ofGag, bothin vitroandin vivo.

The matrix metalloproteinase (MMP) family degrades the extracellular matrix. One member of this family, MMP-1, initiates the breakdown of interstitial collagens. The expression ofMMP-1 is controlled by themitogen activated protein kinase (MAPK) pathway(s) via the activity of acti-vator protein-1 (AP-1) and polyoma enhancing activity-3/ E26 virus (PEA3/ETS) transcription factors through con-sensus binding sites present in the promoter.

Humanb2 -glycoprotein I (b2 GPI), also known as apolipo-protein H, has been implicated in haemostasis and the pro-duction ofanti-phospholipid antibodies. There is a wide range ofinterindividual variation in b2GPI plasma levels that is thought to be under genetic control, but itsmolecular basis remains unknown. To understand the genetic basis of b2GPI variation, we analyzed the 5¢ flanking region ofthe b2GPIgene for mutation detection by DHPLC and identi-fied a point mutation at the transcriptional initiation site ()1CfiA) with a carrier frequency of 12.1%. ...

A survey of plasma proteins in approximately 1300 individuals by MALDI-TOF MS resulted in identification of a structural polymorphism of apolipoprotein C1 (ApoC1) that was found only in persons of American Indian or Mexican ancestry. MS⁄MS analysis revealed that the alteration consisted of a T45S variation.

The DMC1 protein, a meiosis-specific DNA recombinase, promotes homol-ogous pairing and strand exchange. The I37N single nucleotide polymor-phism of the human DMC1 protein was reported as a result of human genome sequencing projects.

Factor VII-activating protease (FSAP) circulates as an inactive zymogen in the plasma. FSAP also regulates fibrinolysis by activating pro-urokinase or cellular activation via cleavage of platelet-derived growth factor BB (PDGF-BB). As the Marburg I polymorphism of FSAP, with reduced enzymatic activity, is a risk factor for atherosclerosis and liver fibrosis, the regulation of FSAP activity is of major importance.

Chitotriosidase (CHIT1) is a chitinase that is secreted by activated macro-phages. Plasma chitotriosidase activity reflects the presence of lipid-laden macrophages in patients with Gaucher disease. CHIT1 activity can be con-veniently measured using fluorogenic 4-methylumbelliferyl (4MU)–chitotri-oside or 4MU–chitobioside as the substrate, however, nonsaturating concentrations have to be used because of apparent substrate inhibition.

Many proteins and peptides can form amyloid-like structures bothin vivo andin vitro. Although strikingly similar fibrillar structures can be observed across a variety of amino acid sequences, the fibrils formed often exhibit a stunning wealth of polymorphisms at the level of electron or atomic force microscopy.

The risk of acquiring variant Creutzfeldt–Jakob disease is closely related to polymorphism at codon 129 of the human prion gene, because almost all variant Creutzfeldt–Jakob disease patients are Met⁄Met homozygotes. Although animal transmission experiments corroborated this seeding dis-crimination, the origin of the differential seeding efficiency of the bovine prion seed for human codon 129 polymorphism remained elusive.