Asymmetric synthesis of (R)-2-[3-(methoxymethoxy)propyl]- 3,3-diphenyl-1-tosyl-1,3-azasilinan-6-one

Azasilanes have excellent bioactivities; however, asymmetric synthesis of azasilinan-6-one with a substitution at the second potion has been investigated very little. In this paper, (R)-2-[3-(methoxymethoxy)propyl] -3,3-diphenyl-1-tosyl-1,3-azasilinan-6-one was successfully synthesized.