Báo cáo Y học: The group I-like ribozyme DiGIR1 mediates alternative processing of pre-rRNA transcripts in Didymium iridis
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During starvation induced encystment, cells of the myxo-myceteDidymiumiridisaccumulate a7.5-kbRNAthat is the result of alternative processing of pre-rRNA. The 5¢ end corresponds to an internal processing site cleaved by the group I-like ribozyme DiGIR1, located within the twin-ribozyme intron Dir.S956-1. The RNAretains the majority ofDir.S956-1 including thehoming endonuclease geneanda small spliceosomal intron, the internal transcribed spacers ITS1 and ITS2, and the large subunit rRNAlacking its two group I introns. ...
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