Đánh giá chất lượng cuộc sống ở bệnh nhân ung thư dạ dày mới chẩn đoán tại Bệnh viện Quân y 103

Stomach cancer remains a leading cause of morbidity and mortality globally, including in Vietnam. While advancements in treatment focus on personalized and multi-modal approaches, assessing the Quality of Life (QoL) has become paramount for a holistic understanding of patient experiences. QoL encompasses not only physical symptoms but also psychological, social, and functional aspects crucial for evaluating treatment effectiveness and patient-centered care. Despite the availability of standardized tools like EORTC QLQ-C30 and QLQ-STO22, comprehensive QoL assessments, especially at initial diagnosis among newly diagnosed stomach cancer patients in Vietnam, remain limited. This gap highlights the urgent need for studies to understand the current QoL status and identify associated factors, thereby informing early intervention strategies.

Medical professionals, oncologists, palliative care specialists, healthcare researchers, and policymakers involved in cancer care.

This cross-sectional descriptive study aimed to evaluate the Quality of Life (QoL) among 120 newly diagnosed stomach cancer patients at Military Hospital 103, utilizing the EORTC QLQ-C30 and QLQ-STO22 instruments, and to identify factors associated with poor QoL. Data encompassing clinical and pathological characteristics alongside QoL scores were collected, and statistical methods including descriptive analysis, comparative analysis, and multivariate regression were employed to determine relevant factors. The study revealed a moderate mean Global Health Status score of 62.57, indicating that while patients maintained good role and social functioning, they experienced significant symptom burdens. Key issues identified by the EORTC QLQ-C30 included insomnia (median 66.7), fatigue (median 22.2), and financial difficulties (mean 42.0). Furthermore, the specific QLQ-STO22 scale highlighted prevalent problems such as anxiety (33.1), dry mouth (31.7), and taste changes (29.4). Multivariate regression analysis identified weight loss ≥10%/6 months (OR=3.0), advanced disease stage III-IV (OR=2.9), and low BMI (OR=2.5) as independent prognostic factors for low QoL. These findings underscore that the QoL of stomach cancer patients is significantly impacted by both physical and emotional symptoms, alongside considerable financial strain. Poor nutritional status and advanced disease progression are critical determinants of a diminished QoL. The study emphasizes the imperative of integrating comprehensive QoL screening and support measures from the point of diagnosis. Such interventions should extend beyond nutritional support to effectively manage symptoms like insomnia, anxiety, oral issues, and financial burdens, ultimately enhancing patients' overall well-being and contributing to patient-centered oncology care in Vietnam.