Chapter 013. Chest Discomfort (Part 7)

Unpublished data from Brigham and Women's Hospital Chest Pain Study, 1997–1999 Markers of myocardial injury are often obtained in the emergency department evaluation of acute chest discomfort. The most commonly used markers are creatine kinase (CK), CK-MB, and the cardiac troponins (I and T). Rapid bedside assays of the cardiac troponins have been developed and shown to be sufficiently accurate to predict prognosis and guide management. Some data support the use of other markers, such as serum myoglobin, C-reactive protein (CRP), placental growth factor, myeloperoxidase, and B-type natriuretic peptide (BNP); their roles are the subject of ongoing research. Single values...