Chapter 023. Weakness and Paralysis (Part 5)

Quadriparesis or Generalized Weakness Generalized weakness may be due to disorders of the CNS or of the motor unit. Although the terms quadriparesis and generalized weakness are often used interchangeably, quadriparesis is commonly used when an upper motor neuron cause is suspected, and generalized weakness when a disease of the motor unit is likely. Weakness from CNS disorders is usually associated with changes in consciousness or cognition, with spasticity and brisk stretch reflexes, and with alterations of sensation. Most neuromuscular causes of generalized weakness are associated with normal mental function, hypotonia, and hypoactive muscle stretch reflexes. The major causes of intermittent weakness...