ĐÁNH GIÁ VÀ KIỂM SOÁT
NGUY CƠ TIM MẠCH
Ở NGƯỜI CÓ BỆNH ĐỘNG MẠCH
NGOẠI VI
HỘI NGHỊ TĂNG HUYẾT ÁP VIỆT NAM LẦN THỨ HAI
Hà nội - 5/2016
TS.BS.Nguyễn Thị Thu Hoài
Viện Tim Mạch Quốc Gia Việt Nam
Prevalence of PAD increases with age
0
10
20
30
40
50
60
55-59 60-64 65-69 70-74 75-79 80-84 85-89
Age group (y)
Figure adapted from Creager M, ed. Management of Peripheral Arterial Disease. Medical, Surgical and Interventional Aspects. 2000.
1 Meijer WT et al. Arterioscler Thromb Vasc Biol 1998; 18: 185-192.
2.Criqui MH et al. Circulation 1985; 71: 510-515.
Patients with PAD (%)
Rotterdam Study (ABI Test <0.9)1 San Diego Study (PAD by noninvasive tests)2
Mortality is very high in patients with
severe PAD
Relative 5-year mortality
1. Criqui MH. Vasc Med 2001; 6 (suppl 1): 3–7.
2. McKenna M et al. Atherosclerosis 1991; 87: 119–28.
3. Ries LAG et al. (eds). SEER Cancer Statistics Review, 1973–1997. US: National Cancer Institute; 2000.
Patients (%)
0
5
10
15
20
25
30
35
40
45
50
Colon/rectal
cancer1
Breast
cancer1
Severe
PAD2
Non-Hodgkin’s
lymphoma3
15
38 44 48
Resnick HE et al. Circulation 2004; 109: 733-739.
There is a strong two-way association
between decreased ABI and increased risk
for cardiovascular death1
Baseline ABI*
Percent
0
20
40
60
70
50
30
10
All-cause mortality
CVD Mortality
*Mean participant follow-up 8.3 years
•10 million people in USA have PDA
•In 1996: 128,588 individuals lost limbs due
to PDA
•Amputation amongs people with PDA: 2,174
people, including many people with diabetes.
•Risk of limb loss due to PDA increased with
age, more in men than women.
PAD and Limb Loss