Báo cáo khoa học: Infrared spectroscopy as a tool for discrimination between sensitive and multiresistant K562 cells
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Fourier transform infrared spectroscopy was performed on human leukemic daunorubicin-sensitiveK562 cells and their multiresistant counterpart derived by selection. Statistical analysis, including variable reduction and linear discrimi-nant analysis was performed on sensitive and multiresistant cells spectra in order to establish a diagnostic tool for multiresistant pattern. For each of the twomethods of data reduction tested [genetic algorithm or principal component analysis (PCA)] discriminationbetween the twocell lineswas found to be possible....
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