Facile multi-components one-pot synthesis of dipyrazolo[1,5-a:3',4'-d]pyrimidine as potent bioactive scaffolds

An efficient, three-component, catalyst free synthesis of dipyrazolo[1,5-a:3',4'-d]pyramid scaffolds has been carried out using 3-methyl-1H-pyrazol-5(4H)-one (1), 5-amino pyarazole (2a-b) and substituted aromatic aldehydes.