Kết quả điều trị dọa sảy thai dưới 12 tuần và một số yếu tố liên quan tại Bệnh viện Phụ sản Thái Bình năm 2024

Threatened miscarriage, an early pregnancy complication marked by vaginal bleeding and lower abdominal pain, is a common global obstetric challenge. This critical condition, which can severely impact both maternal physical and psychological well-being, often requires immediate and effective intervention to preserve the pregnancy. Despite existing treatment protocols, variations in clinical management and prognostic assessment highlight the need for clearer guidelines. Understanding the efficacy of current approaches and identifying influencing factors is crucial for improving patient care. This study evaluates the treatment outcome of threatened miscarriage under 12 weeks and identifies related factors at Thai Binh Hospital of Obstetrics and Gynecology, aiming to enhance clinical decision-making and patient counseling.

Healthcare professionals, specifically obstetricians, gynecologists, general practitioners involved in prenatal care, medical researchers, and students in obstetrics and gynecology.

This prospective cross-sectional descriptive study investigated the treatment outcomes of threatened miscarriage in 151 pregnant women diagnosed at ≤ 12 weeks of gestation, who received care at Thai Binh Hospital of Obstetrics and Gynecology between January and June 2024. The primary objective was to assess the overall success rate of interventions and identify related factors associated with treatment failure. The methodology involved collecting and analyzing demographic, obstetric history, and treatment data, including the use of progesterone and antibiotics, and employing univariate regression analysis to determine statistical significance. The study revealed a high overall treatment success rate of 90.7% for threatened miscarriage. However, regression analysis identified two statistically significant independent prognostic factors for treatment failure: maternal age ≥ 35 years (Odds Ratio = 10.53; p < 0.05) and a history of miscarriage or stillbirth (Odds Ratio = 13.12; p < 0.05). Notably, specific treatment methods, such as the addition of hemostatic agents or antibiotics, or the combination of Progesterone with Estrogen, did not show a statistically significant difference in treatment success rates. The findings underscore the effectiveness of current management strategies for early-stage threatened miscarriage at the hospital. Crucially, the identification of advanced maternal age and a history of prior pregnancy loss as strong predictors of treatment failure provides actionable insights. These results imply a critical need for enhanced monitoring, individualized counseling, and potentially more targeted interventions for these high-risk groups to further improve treatment outcome and support successful pregnancies. This research contributes to evidence-based practice in obstetrics, facilitating better risk stratification and patient management.