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Báo cáo khóa học: Expressed protein ligation Method and applications

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:15

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The introduction of noncanonical amino acids and bio-physical probes into peptides and proteins, and total or segmental isotopic labelling has the potential to greatly aid thedeterminationofproteinstructure, functionandprotein– protein interactions.To obtain a peptide as large as possible by solid-phase peptide synthesis, native chemical ligation was introduced to enable synthesis of proteins of up to 120 amino acids in length.

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