intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

37
lượt xem
2
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

The major components of neuritic plaques found in Alzheimer disease (AD) are peptides known as amyloid b-peptides (Ab),which derive from the proteolitic cleavage of theamyloidprecursorproteins.InvitroAbmayundergoa conformational transition from a soluble form to aggrega-ted,fibrillary b-sheet structures,which seem to be neuro-toxic. Alternatively,it has been suggested that ana-helical form can be involved in a process of membrane poration, which would then trigger cellular death.

Chủ đề:
Lưu

Nội dung Text: Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2