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Báo cáo khoa học: The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis Implications for the substrate activation mechanism of this enzyme
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The crystal structure of pyruvate decarboxylase fromKluyveromyces lactis has been determined to 2.26 A˚ resolution. Like other yeast enzymes, Kluyveromyces lactispyruvate decarboxylase is subject to allosteric sub-strate activation. Binding of substrate at a regulatory site induces catalytic activity.
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