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INTRODUCTION
Osteogenesis imperfecta (OI) is a congenital disorder of the bone.
The cause of the disease is a mutation in the type I collagen synthesis
gene that makes bones fragile and deformed.
In the world, there have been many researches on surgical treatments
with the aim of cutting the orthostatic bone structure and fixing
broken bones to improve quality of life, limiting fractures.
Vietnam has not had a comprehensive study of epidemiological
characteristics, clinical symptoms, subclinical and results of
treatment of OI. Medical treatment does not improve motor skills.
Therefore, the daily life problem of the patient still depends on the
family and the medical staff.
From the above reasons, we conduct research topic "Study of
clinical, subclinical features and corrective surgery outcomes of
lower limb axis in patients with Osteogenesis imperfecta" with the
following two objectives:
1. Surveying some clinical features and X-ray images of long bones,
skulls, spine, blood biochemical tests and electrolytes in patients with
Osteogenesis imperfecta.
2. Evaluation of internal bone results using self-made tool to treat
deformation of the lower limbs in patients with Osteogenesis
imperfecta at Military Hospital 7 A.
NEW CONTRIBUTIONS OF THE THESIS
1. Evaluate in detail clinical features, X-ray images of long bones,
flat bones, spine bones, biochemical tests of blood and electrolytes in
patients suffering from Osteogenesis imperfecta.
