Quantitative HBV-DNA and determination of drug-resistant mutants in patients with chronic hepatitis B virus (HBV) in Hai Duong province

After 6 months of treatment with antiretroviral drugs based on quantitative HBV-DNA. The rate of normalization of liver enzymes increased significantly. The rate of patients with quantitative HBV-DNA under the detectable level was highly significant. Patients with mutations in the RT region was highly significant (52.9%) while we did not identify any mutations in the Pre-S region.