Summary of organic chemistry doctoral thesis: Design, synthesis and evaluation of acetylcholinesterase inhibitory activity of chalcone derivatives for the discovery of new anti-alzheimer drugs

The objectives of the thesis: Molecular docking studies on acetylcholinesterase were performed to predict the chalcone structure has good in silico AChE acetylcholinesterase inhibitory activity. The potential chalcone compounds were synthesized and studied for their in vitro and in vivo AChE inhibitory activities