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Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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Recent and increasing use of computational tools in the field of nicotinic receptors has led to the publication of several models of ligand–receptor interactions. Thesemodels are all basedon the crystal structure at 2.7 A˚ resolutionof aprotein related to the extracellular N-terminus of nicotinic acetyl-choline receptors (nAChRs), the acetylcholine binding pro-tein. In the absence of any X-ray or NMR information on nAChRs, this new structure has provided a reliable alter-native to study the nAChR structure....

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Nội dung Text: Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors

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