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Báo cáo khoa học: Interaction with calmodulin is important for the secretion of thimet oligopeptidase following stimulation
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Thimet oligopeptidase (EC 3.4.24.15; EP24.15) was originally described as a neuropeptide-metabolizing enzyme, highly expressed in the brain, kidneys and neuroendocrine tissue. EP24.15 lacks a typical signal peptide sequence for entry into the secretory pathway and is secreted by cells via an uncon-ventional and unknown mechanism.
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