Study on toxicities of 10β-[(2'β-hydroxy-3'- imidazol) propyl] deoxo-artemisinin (32) in reproductive and developmental progresses of mice

OECD guidelines were applied. Mice were divided into 7 groups consisting of 30 females and 10 males each. In which, the control group received the solvent, only females or males in 4 other groups were taken the testing samples (32), and both females and males of 2 remain groups were given those samples. Mice were given oral samples at a dose of 288 or 576 mg/kg/day × 7 consecutive days depending on individual group.