Health and disease

objectives: To identify the state of heavy metal pollution in water and food in two coastal communes of Thuy nguyen District, Haiphong city in 2017- 2018. To describe the pattern of disease and the risk due to exposure to heavy metal contamination among community residents in the study area.

27p extraenglish 24-05-2021 22 4   Download

Campylobacter species are a leading cause of food-borne disease and C. jejuni highlight the most potential public health impact of Campylobacter contamination by pathogens originating from animals or animal products.. The total of 33meat samples comprising 8 from sheep (5) and goat (3) also 25 beef samples were screened by morphological, biochemical and molecular technique.

9p chauchaungayxua11 23-03-2021 17 2   Download

This study is undertaken with the objectives, to find the practices of health and hygiene among school children in Mangalore city and to compare the practices on health and hygiene between Government, Private and Aided school children.

5p guineverehuynh 18-06-2020 21 2   Download

The objective of the thesis is to know about two species of SLP P.heterotremus and P. westermani, providing a scientific basis for the diagnosis and prevention of SLP disease, contributing to protecting public health.

27p xacxuoc4321 11-07-2019 56 4   Download

Researching this thesis with a view to: describe the knowledge, attitude and practice (KAP) of farmer exposure to pesticides; determine disease model and describe some factors related to farmer health in cultivating tea; construction and appreciate of effect of interfere model on human health protection suitably for current conditions in Thai Nguyen.

24p nguyenthiminh32 12-07-2014 131 5   Download

3-Hydroxyacyl-CoA dehydrogenase (HAD) functions in mitochondrial fatty acid b-oxidation by catalyzing the oxidation of straight chain 3-hyd-roxyacyl-CoAs. HAD has a preference for medium chain substrates, whereas short chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) acts on a wide spectrum of substrates, including steroids, cholic acids, and fatty acids, with a preference for short chain methyl-branched acyl-CoAs.

10p fptmusic 12-04-2013 34 3   Download

Endothelial cells are indispensable components of the vascular system, and play pivotal roles during development and in health and disease. Their properties have been studied extensively byin vivo analysis of genetically modified mice.

11p media19 06-03-2013 56 3   Download

MINIREVIEW Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease Rafael Pulido1 and Rob Hooft van Huijsduijnen2 ´ ´ 1 Centro de Investigacion Prıncipe Felipe, Valencia, Spain 2 Merck Serono International, Geneva, Switzerland Keywords arthritis; asthma; cancer; laforin; multiple sclerosis; myoclonus epilepsy; myotubular myopathy; protein phosphorylation ⁄ dephosphorylation; PTEN; signal transduction Correspondence ´ ´ R.

19p media19 05-03-2013 42 3   Download

Angiotensin-converting enzyme (ACE) and its homologue angiotensin-converting enzyme 2 (ACE2) are critical counter-regulatory enzymes of the renin–angiotensin system, and have been implicated in cardiac function, renal disease, diabetes, atherosclerosis and acute lung injury.

10p vinaphone15 28-02-2013 39 3   Download

Alzheimer’s disease (AD) is a neurological disorder characterized by the presence of amyloidb(Ab) peptide fibrils and oligomers in the brain. It has been suggested that soluble Ab oligomers, rather than Ab fibrils, contribute to neurodegeneration and dementia due to their higher level of toxicity.

12p vinaphone15 28-02-2013 34 2   Download

The last decade has seen clear links emerge between the genetic determi-nants and neuropathological hallmarks of parkinsonism and dementia, notably with the discovery of mutations ina-synuclein and tau. Following the description of mutations in LRRK2 linked to Parkinson’s disease, char-acterized by variable pathology including eithera-synuclein or tau deposi-tion, it has been suggested that LRRK2 functions as an upstream regulator of Parkinson’s disease pathogenesis.

10p vinaphone15 28-02-2013 29 3   Download

Rare, inherited mutations causing familial forms of Parkinson’s disease have provided insight into the molecular mechanisms that underlie the genetic and sporadic forms of this disease. Loss of protein function result-ing from autosomal-recessive mutations in PTEN-induced putative kinase 1 (PINK1), Parkin and DJ-1 has been linked to mitochondrial dysfunction, accumulation of abnormal and misfolded proteins, impaired protein clear-ance and oxidative stress.

9p vinaphone15 28-02-2013 39 3   Download

Aggregation of the normal cellular prion protein, PrP, is important in the pathogenesis of prion disease. PrP binds glycosaminoglycan (GAG) and divalent cations, such as Cu 2+ and Zn 2+ . Here, we report our findings that GAG and Cu 2+ promote the aggregation of recombinant human PrP (rPrP).

12p vinaphone15 28-02-2013 42 4   Download

Plant cathepsin B-like cysteine protease (CBCP) plays a role in disease resistance and in protein remobilization during germination. The ability of animal cathepsin B to function as a dipeptidyl carboxypeptidase has been attributed to the presence of a dihistidine (His110-His111) motif in the occluding loop, which represents a unique structure of cathepsin B.

15p vinaphone15 28-02-2013 44 2   Download

The amyloidbpeptide (Ab) with 39–42 residues is the major component of amyloid plaques found in brains of Alzheimer’s disease patients, and solu-ble oligomeric peptide aggregates mediate toxic effects on neurons. The Ab aggregation involves a conformational change of the peptide structure to b-sheet.

9p vinaphone15 28-02-2013 45 3   Download

Classic Elite Yarns is proud to participate in Stitch Red, a fastgrowing campaign to “stick it to heart disease” started by Jimmy Beans Wool and supported by many in the needlearts industry. When you buy our designated Stitch Red yarns, CEY will donate 5% of proceeds to the Foundation for the National Institutes of Health (FNIH) in support of The Heart Truth®. Joining thousands of knitters and crocheters by supporting Stitch Red, and help raise awareness and prevent heart disease in women. To learn more about Stitch Red, visit www.stitchred.com and see how you can get involved!...

3p new_would 28-02-2013 58 8   Download

The expression of proteoglycans (PGs), essential macromolecules of the tumor microenvironment, is markedly altered during malignant transforma-tion and tumor progression. Synthesis of stromal PGs is affected by factors secreted by cancer cells and the unique tumor-modified extracellular matrix may either facilitate or counteract the growth of solid tumors.

20p viettel02 19-02-2013 52 4   Download

Heparanase is an endo-b-D-glucuronidase capable of cleaving heparan sul-fate side chains at a limited number of sites, yielding heparan sulfate frag-ments of still appreciable size. Importantly, heparanase activity correlates with the metastatic potential of tumor-derived cells, attributed to enhanced cell dissemination as a consequence of heparan sulfate cleavage and remod-eling of the extracellular matrix and basement membrane underlying epithe-lial and endothelial cells.

14p viettel02 19-02-2013 43 3   Download

Proteolytic processes in the extracellular matrix are a major influence on cell adhesion, migration, survival, differentiation and proliferation. The syndecan cell-surface proteoglycans are important mediators of cell spread-ing on extracellular matrix and respond to growth factors and other bio-logically active polypeptides.

14p viettel02 19-02-2013 43 4   Download

The small leucine-rich proteoglycans (SLRPs) are involved in many aspects of mammalian biology, both in health and disease. They are now being rec- ognized as key signaling molecules with an expanding repertoire of molecu- lar interactions affecting not only growth factors, but also various receptors involved in controlling cell growth, morphogenesis and immunity.

12p viettel02 19-02-2013 46 3   Download