Important role

This article analyses the role of digital transformation in the national education system, the importance of digital transformation for open education in the current period, and the relationship between open education and digital citizenship. On that basis, the author proposes implementing digital transformation in open education to serve digital citizenship training.

9p viwalton 02-07-2024 0 0   Download

Public parks in cities, with most of their area being green areas, play an important role not only in balancing the living environment, but also in contributing to the minimisation of flood risks through absorption and the storing of water. This creates the motivation to restore, maintain and develop green areas in inner cities, especially in centralised areas, which have a high level of urbanisation potentially associated with a shortage of such green-lands.

6p viwalton 02-07-2024 0 0   Download

Oesophageal squamous cell carcinoma is one of the most commonly diagnosed carcinomas in China, and postoperative radiotherapy plays an important role in improving the prognosis of patients. Carcinomas in different locations of the oesophagus could have different patterns of lymph node metastasis after surgery.

8p vishanshan 27-06-2024 2 1   Download

In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, two-sample Mendelian randomization (MR) approach to investigate the causal relationship between systemic inflammatory cytokines and myeloproliferative neoplasms.

12p vishanshan 27-06-2024 1 1   Download

Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during which LXR as a 25-HC receptor plays an important role.

14p vishanshan 27-06-2024 2 1   Download

Gliomas are the most common primary intracranial tumor worldwide. The maintenance of telomeres serves as an important biomarker of some subtypes of glioma. In order to investigate the biological role of RTEL1 in glioma.

15p vishanshan 27-06-2024 1 1   Download

The androgen/androgen receptor (AR)-signaling axis plays a central role in prostate cancer (PCa). Upon androgen-binding the AR dimerizes with another AR, and translocates into the nucleus where the AR-dimer activates/inactivates androgen-dependent genes. Consequently, treatments for PCa are commonly based on androgen deprivation therapy (ADT).

13p vishanshan 27-06-2024 2 1   Download

Most cancer patients ultimately die from the consequences of distant metastases. As metastasis formation consumes energy mitochondria play an important role during this process as they are the most important cellular organelle to synthesise the energy rich substrate ATP, which provides the necessary energy to enable distant metastasis formation.

14p vishanshan 27-06-2024 2 1   Download

The role of clinical breast examination (CBE) for early detection of breast cancer is extremely important in lower-middle-income countries (LMICs) where access to breast imaging is limited. Our study aimed to describe the outcomes of a community outreach breast education, home CBE and referral program for early recognition of breast abnormalities and improvement of breast cancer awareness in a rural district of Pakistan.

10p vishanshan 27-06-2024 2 1   Download

Part 1 of ebook "Integrated construction information" provides readers with contents including: Part One - What is integration and why is it important; Part Two - The history of construction integration; Part Three - Product modelling;...

263p mothoiphong 28-06-2024 1 1   Download

Youth healthcare has an important role in promoting a healthy lifestyle in young children in order to prevent lifestyle-related health problems. To aid youth healthcare in this task, a new lifestyle screening tool will be developed. The aim of this study was to explore how youth healthcare professionals (YHCP) could best support parents in improving their children’s lifestyle using a new lifestyle screening tool for young children.

9p vishanshan 27-06-2024 1 1   Download

Healthcare staff deliver patient care in emotionally charged settings and experience a wide range of emotions as part of their work. These emotions and emotional contexts can impact the quality and safety of care. Despite the growing acknowledgement of the important role of emotion, we know very little about what triggers emotion within healthcare environments or the impact this has on patient safety.

13p vishanshan 27-06-2024 1 1   Download

Despite word-of-mouth (WOM) and electronic WOM (eWOM) influencing people’s willingness to donate blood, no research has explored this behavior among blood service employees who are also donors. This underexplored segment is highly important, as they are generally committed to both the organization and the cause and are likely more informed on the topic of blood donation than the average donor.

12p vishanshan 27-06-2024 1 1   Download

Current and former dementia policies in the United Kingdom (UK) recommend diagnosing dementia early, or as close to the onset of symptoms as possible. Informal caregivers play an important role in initiating the diagnostic process and providing support to people living with dementia.

11p vishanshan 27-06-2024 2 1   Download

Part 1 of ebook "Tourism management, marketing, and development (Volume I: The importance of networks and ICTs)" provides readers with contents including: ICT and tourism; tourism branding, identity, reputation co-creation, and word-of-mouth in the age of social media; technological innovation in e-tourism; open data challenges and opportunities for the tourism industry; the role of ICT within tourism development processes in post industrial sites; e-reputation management and strategic business development using web 2.0 tools;...

137p giangmacvien 22-06-2024 4 1   Download

Postoperative central diabetes insipidus (CDI) is commonly observed in craniopharyngioma (CP) patients, and the inflammatory response plays an important role in CPs. We aimed to evaluate the predictive value of preoperative peripheral inflammatory markers and their combinations regarding CDI occurrence in CPs.

9p vishanshan 27-06-2024 2 1   Download

Basement membrane (BM) is an important component of the extracellular matrix, which plays an important role in the growth and metastasis of tumor cells. However, few biomarkers based on BM have been developed for prognostic assessment and prediction of immunotherapy in bladder cancer (BLCA).

13p vikoch 27-06-2024 1 1   Download

Cancer-associated fibroblasts (CAFs) play an important role in the tumor microenvironment. Despite the well-known in vitro antitumoral efect of vitamin D3 (VD3), its impact on breast CAFs is almost unknown. In this study, we analyzed the ex vivo effects of calcitriol on CAFs isolated from breast cancer tissues.

25p vikoch 27-06-2024 1 1   Download

Lactate dehydrogenase (LDHs) is an enzyme involved in anaerobic glycolysis, including LDHA, LDHB, LDHC and LDHD. Given the regulatory role in the biological progression of certain tumors, we analyzed the role of LDHs in pan-cancers.

20p vikoch 27-06-2024 1 1   Download

Ovarian cancer (OC) is a complex disease with significant tumor heterogeneity with the worst prognosis and highest mortality among all gynecological cancers. Glycosylation is a specific post-translational modification that plays an important role in tumor progression, immune escape and metastatic spread. The aim of this work was to identify the major glycosylation-related genes (GRGs) in OC and construct an effective GRGs signature to predict prognosis and immunotherapy.

16p vikoch 27-06-2024 1 1   Download