Pathological factors

Objectives: Identifying the species, distribution, biological characteristics and influential factors to the liver flukes infection rate in cattle the Mekong Delta. Suggesting the treatment methods for infected cattle in Mekong Delta.

25p cotithanh321 06-08-2019 44 4   Download

The objective of the research is: To determine the prevalence of vitamin D insufficiency in pregnant women at the National Hospital of Gynecology & Obstetrics and the National Hospital of Endocrinology; to explore relationships between plasma 25 hydroxy vitamin D concentration in women with gestational diabetes mellitus.

29p change04 08-06-2016 29 4   Download

Metallothioneins (MTs) constitute a family of cysteine-rich metalloproteins involved in cytoprotection during pathology. In mammals there are four isoforms (MT-I )IV), of which MT-I and -II (MT-I + II) are the best characterized MT proteins in the brain. Accumulating studies have demon-strated MT-I + II as multipurpose factors important for host defense responses, immunoregulation, cell survival and brain repair.

14p inspiron33 26-03-2013 30 4   Download

Amyloid-b(Ab) aggregation and amyloid formation are key pathological features of Alzheimer’s disease, and are considered to be two of the major contributing factors to neurodegeneration and dementia. Identification of small molecule inhibitors that are orally available, have low toxicity and high central nervous system bioavailability is one approach to the potential development of a disease-modifying treatment for Alzheimer’s disease.

12p media19 06-03-2013 49 2   Download

Vascular endothelial growth factor (VEGF) family members play impor-tant roles in embryonic development and angiogenesis during wound healing and in pathological conditions such as tumor formation. Parapox-viruses express a new member of the VEGF family which is a functional mitogen that specifically activates VEGF receptor (VEGFR)-2 but not VEGFR-1.

11p media19 05-03-2013 28 3   Download

Nuclear factor-kappaB (NF-jB) has been proposed to serve a dual func-tion as a regulator of neuron survival in pathological conditions associated with neurodegeneration. NF-jB is a transcription family of factors com-prising five different proteins, namely p50, RelA⁄p65, c-Rel, RelB and p52, which can combine differently to form active dimers in response to external stimuli.

9p vinaphone15 27-02-2013 26 3   Download

The angiogenic process in the central nervous system (CNS) is basically regulated by typical angiogenic signaling systems such as vascular endothe-lial growth factor (VEGF)–VEGF receptors and angiopoietin–Tie recep-tors. In addition to regular endothelial–pericyte interaction, the CNS vasculature has a unique system of cell to cell communication between endothelial cells and astrocytes which is known as the blood–brain barrier.

8p vinaphone15 25-02-2013 37 3   Download

Thrombin generation increases in several pathological conditions, including cancer, thromboembolism, diabetes and myeloproliferative syndromes. During tumor development, thrombin levels increase along with several other molecules, including cytokines and angiogenic factors. Under such conditions, it is reasonable to predict that thrombin may recognize new low-affinity substrates that usually are not recognized under low-expression levels conditions.

13p viettel02 22-02-2013 36 3   Download

Accumulation ofb-amyloid protein (Ab) is one of the most important pathological features of Alzheimer’s disease. Although Abinduces neurode-generation in the cortex and hippocampus through several molecular mech-anisms, few studies have evaluated the modulation of transcription factors during Ab-induced neurotoxicity.

10p viettel02 19-02-2013 38 3   Download

Arsenic is a strong stimulus of heme oxygenase (HO)-1 expression in experimental studies in response to oxidative stress caused by a stimulus. A functional GT-repeat polymorphism in the HO-1 gene promoter was inversely correlated to the development of coronary artery disease in diabetics and development of restenosis following angioplasty in patients. The role of this potential vascular protective factor in carotid atherosclerosis remains unclear. We previously reported a graded association of arsenic...

11p toshiba23 18-11-2011 89 2   Download